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Table 1 The table displays the population size and mean ± standard deviation of age at diagnosis, LT4 starting dose, height (H) at puberty onset, heigth gain during puberty, final height (FH), and target height (TH) in the recruited patients classified as etiology and gender. a vs males: p = 0.009

From: Final height in Italian patients with congenital hypothyroidism detected by neonatal screening: a 20-year observational study

 

In situ thyroid

Ectopic gland

Athyreosis

Males

Females

Study cohort

Number of patients (%)

44 (20.5 %)

109 (50.7 %)

62 (28.8 %)

63 (29.3 %)

152 (70.7 %)

215 (100 %)

Age at diagnosis (days)

25.4 ± 10.1

24.1 ± 6.8

26.6 ± 15.1

24.7 ± 11.7

25.2 ± 10.0

25.1 ± 10.5

LT4 starting dose (μg/kg/day)

8.9 ± 2.8

8.8 ± 3.0

8.6 ± 3.0

8.1 ± 2.7

9.1 ± 3.0

8.8 ± 2.9

H at puberty onset (SDS)

-0.3 ± 1.0

0.1 ± 0.9

-0.2 ± 0.9

-0.1 ± 0.9

-0.1 ± 1.0

-0.1 ± 1.0

Pubertal H gain (SDS)

0.1 ± 0.7

-0.2 ± 0.8

0.1 ± 0.8

-0.2 ± 0.8

0.0 ± 0.8

-0.1 ± 0.8

FH (SDS)

-0.2 ± 1.0

-0.1 ± 1.0

-0.1 ± 1.1

-0.3 ± 1.0

-0.1 ± 1.0

-0.1 ± 1.0

TH (SDS)

-1.0 ± 1.0

-0.8 ± 0.9

-0.7 ± 1.0

-1.0 ± 0.8

-0.7 ± 1.0a

-0.8 ± 1.0

  1. Data cohort according to aetiology and gender