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Table 2 The Table displays mean ± standard deviation of age at diagnosis, starting dose of levo-thyroxine (LT4), height (H) at puberty onset, final height (FH), and target height (TH) in the recruited patients divided in quartiles on the basis of birthdate. a vs 4 th quartile p ≤ 0.001; b vs 4 th quartile p ≤ 0.005; c vs 1st quartile and vs 2nd quartile p < 0.05

From: Final height in Italian patients with congenital hypothyroidism detected by neonatal screening: a 20-year observational study

  1st quartile, 54 patients (18-Mar-80/9-Nov-84) 2nd quartile, 54 patients (30-Nov-84/23-Jun-90) 3rd quartile, 54 patients (29-Jul-90/27-Jan-95) 4th quartile, 53 patients (27-Feb-95/9-Dec-00)
Age at diagnosis (days) 28.5 ± 11.9 a 27.6 ± 12.6 b 23.4 ± 7.3 20.8 ± 7.4
Starting LT4/kg/day (μg) 7.5 ± 2.4 a 7.6 ± 2.3 a 8.9 ± 2.4 a, c 11.2 ± 3.0
H at puberty onset (SDS) -0.2 ± 1.0 0.0 ± 1.0 0.0 ± 1.0 -0.1 ± 0.8
FH (SDS) -0.1 ± 1.1 0.0 ± 1.1 -0.1 ± 1.0 -0.3 ± 0.9
TH (SDS) -1.0 ± 0.9 a -0.9 ± 1.2 -0.7 ± 0.8 -0.5 ± 0.9
  1. Data according to quartile for birthdate