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Table 1 Sex, ages, thyrotropin (TSH), free thyroxine (FT4) and thyroid autoantibody serum levels in the 12 patients of our series at diagnosis of both Hashimoto’s thyroiditis (HT) and Graves’ disease (GD)

From: Metamorphic thyroid autoimmunity in Down Syndrome: from Hashimoto’s thyroiditis to Graves’ disease and beyond

Patients Sex Age (years) TSHa (mU/l) FT4b (pmol/l) TPOAbsc (IU/ml) TgAbsd (IU/ml) TRABse (IU/l)
1 F HT 3.0 7.10 12.6 95 60 <1.0
GD 5.5 0.0500 45.1 796 150 23.4
2 F HT 3.0 19.56 9.9 1310 182 <1.0
GD 9.0 0.0500 36.8 1300 79 19.0
3 F HT 3.3 0.07 24.6 57 187 <1.0
GD 4.0 0.0060 47.8 44 148 85.0
4 M HT 4.0 8.80 16.8 180 120 <1.0
GD 9.9 0.0500 66.1 278 199 32.7
5 F HT 4.0 5.30 12.1 26 28 <1.0
GD 8.8 0.0001 41.9 149 758 25.2
6 M HT 5.0 0.05 50.0 284 35 <1.0
GD 6.1 0.0500 41.6 189 170 22.0
7 F HT 5.9 5.10 17.4 75 302 <1.0
GD 11.1 0.0100 31.6 248 55 28.0
8 F HT 6.0 8.20 10.5 144 104 <1.0
GD 9.0 0.0500 26.0 39 3 21.0
9 M HT 8.0 0.01 38.0 278 199 <1.0
GD 10.0 0.0050 58.7 278 199 32.7
10 M HT 9.7 9.10 11.0 37 2 <1.0
GD 13.2 0.0200 29.4 200 200 23.0
11 M HT 10.0 8.10 10.5 22 119 <1.0
GD 15.0 0.0010 34.4 45 220 16.0
12 F HT 13.5 4.30 18.0 23 109 1.0
GD 20.0 0.0060 25.0 61 117 31.4
  1. anormal range 0.3–4.5 bnormal range 10.3–24.4
  2. cThyroid peroxidase autoantibodies (normal values <20)
  3. dThyroglobulin autoantibodies (normal values <30)
  4. eTSH receptor autoantibodies (normal values <1.0)
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