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Table 1 Sex, ages, thyrotropin (TSH), free thyroxine (FT4) and thyroid autoantibody serum levels in the 12 patients of our series at diagnosis of both Hashimoto’s thyroiditis (HT) and Graves’ disease (GD)

From: Metamorphic thyroid autoimmunity in Down Syndrome: from Hashimoto’s thyroiditis to Graves’ disease and beyond

Patients

Sex

Age (years)

TSHa (mU/l)

FT4b (pmol/l)

TPOAbsc (IU/ml)

TgAbsd (IU/ml)

TRABse (IU/l)

1

F

HT 3.0

7.10

12.6

95

60

<1.0

GD 5.5

0.0500

45.1

796

150

23.4

2

F

HT 3.0

19.56

9.9

1310

182

<1.0

GD 9.0

0.0500

36.8

1300

79

19.0

3

F

HT 3.3

0.07

24.6

57

187

<1.0

GD 4.0

0.0060

47.8

44

148

85.0

4

M

HT 4.0

8.80

16.8

180

120

<1.0

GD 9.9

0.0500

66.1

278

199

32.7

5

F

HT 4.0

5.30

12.1

26

28

<1.0

GD 8.8

0.0001

41.9

149

758

25.2

6

M

HT 5.0

0.05

50.0

284

35

<1.0

GD 6.1

0.0500

41.6

189

170

22.0

7

F

HT 5.9

5.10

17.4

75

302

<1.0

GD 11.1

0.0100

31.6

248

55

28.0

8

F

HT 6.0

8.20

10.5

144

104

<1.0

GD 9.0

0.0500

26.0

39

3

21.0

9

M

HT 8.0

0.01

38.0

278

199

<1.0

GD 10.0

0.0050

58.7

278

199

32.7

10

M

HT 9.7

9.10

11.0

37

2

<1.0

GD 13.2

0.0200

29.4

200

200

23.0

11

M

HT 10.0

8.10

10.5

22

119

<1.0

GD 15.0

0.0010

34.4

45

220

16.0

12

F

HT 13.5

4.30

18.0

23

109

1.0

GD 20.0

0.0060

25.0

61

117

31.4

  1. anormal range 0.3–4.5 bnormal range 10.3–24.4
  2. cThyroid peroxidase autoantibodies (normal values <20)
  3. dThyroglobulin autoantibodies (normal values <30)
  4. eTSH receptor autoantibodies (normal values <1.0)