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Table 1 Performance of the both specimens using TB assays in detection of pediatric pulmonary TB

From: Comparison of bronchial brushing and sputum in detection of pediatric pulmonary tuberculosis

  Sensitivity (95 % CI) Specificity (95 % CI)
  Bronchial brushing Sputum Bronchial brushing Sputum
AFB smear 29.6 % (15.9–48.5 %) 33.3 % (18.6–52.2 %) 100 % (86.2–100 %) 100 % (86.2–100 %)
Mycobacterial cutlrue 37.0 % (21.5–55.8 %) 44.4 % (27.6–62.7 %) 100 % (86.2–100 %) 100 % (86.2–100 %)
Real–time PCR 33.3 % (18.6–52.2 %) 33.3 % (18.6–52.2 %) 91.7 % (74.2–97.7 %) 100 % (86.2–100 %)
Combination 48.2 % (30.7–66.0 %) 55.6 % (37.3–72.4 %) 100 % (86.2–100 %) 100 % (86.2–100 %)
  1. CI confidence interval, AFB acid-fast bacilli, PCR polymerase chain reaction