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Table 2 Underlying predisposing diseases in children with a history of recurrent pneumonia (RP), with and without non-cystic fibrosis bronchiectasis (non-CF BE)

From: Children with recurrent pneumonia and non-cystic fibrosis bronchiectasis

 

RP and non-CF BE (n = 21)

RP alone (n = 21)

P-value*

OR (95 % CI)**

Chronic rhinosinusitis with post-nasal drip

    

 No

4 (19.0 %)

6 (28.6 %)

 

1 (ref)

 Yes

17 (81.0 %)

15 (71.4 %)

0.47

1.40 (0.30-6.45)

Atopy

    

 No

8 (38.1 %)

9 (42.9 %)

 

1 (ref)

 Yes

13 (61.9 %)

12 (57.1 %)

0.75

0.79 (0.20-3.21)

Total IgE at diagnosis, KU/L

291.8 ± 363.1

278.5 ± 20.9

0.60

 

Sensitisation to perennial allergens

    

 No

14 (66.7 %)

17 (81.0 %)

 

1 (ref)

 Yes

7 (33.3 %)

4 (19.0 %)

0.29

1.81 (0.41-7.93)

Wheezing

    

 No

6 (28.6 %)

3 (14.3 %)

 

1 (ref)

 Yes

15 (71.4 %)

18 (85.7 %)

0.45

0.31 (0.06-1.69)

IgA deficiency

    

 No

18 (85.7 %)

18 (85.7 %)

 

1 (ref)

 Yes

3 (14.3 %)

3 (14.3 %)

1

0.83 (0.14-5.09)

Primary ciliary dyskinesia

    

 No

20 (95.2 %)

21 (100 %)

  

 Yes

1 (4.8 %)

0

1

NC

Middle lobe syndrome

    

 No

14 (66.7 %)

11 (52.4 %)

 

1 (ref)

 Yes

7 (33.3 %)

10 (47.6 %)

0.35

0.66 (0.18-2.45)

Heart disease

    

 No

18 (85.7 %)

18 (85.7 %)

 

1 (ref)

 Yes

3 (14.3 %)

3 (14.3 %)

1

1.71 (0.26-11.2)

Tuberculosis infection

    

 No

21 (100.0 %)

21 (100.0 %)

  

 Yes

0

0

1

NC

Foreign body retention

    

 No

21 (100.0 %)

21 (100.0 %)

  

 Yes

0

0

1

NC

  1. OR odds ratio, CI confidence interval, NC not computable
  2. 2 or Fisher’s exact test (categorical variables); Wilcoxon’s rank-sum test (continuous variables). **ORs from logistic regression models, adjusting for age at diagnosis