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Table 3 Clinical history of lower respiratory tract involvement and lung function test results in children with a history of recurrent pneumonia (RP), with and without non-cystic fibrosis bronchiectasis (non-CF BE)

From: Children with recurrent pneumonia and non-cystic fibrosis bronchiectasis

 

RP and non-CF BE

RP alone

P-value*

OR (95 % CI)**

Mean age ± SD at first pneumonia episode, years

2.0 ± 1.2

1.8 ± 1.6

0.35

1.07 (0.51-2.23)

Mean number of pneumonia episodes before HRCT ± SD

4.0 ± 3.2

4.1 ± 2.3

0.30

0.65 (0.34-1.25)

Mean number of wheezing events per year ± SD

4.5 ± 2.9

5.0 ± 3.3

0.60

0.90 (0.45-1.81)

First available lung function test results:

    

 FVC (% of predicted value)

91.1 ± 15.8

100.5 ± 10.6

0.13

0.52 (0.24-1.13)

 FEV1 (% of predicted value)

77.9 ± 17.8

96.8 ± 12.4

0.004

0.24 (0.07-0.78)

 FEF25–75 (% of predicted value)

69.3 ± 25.6

89.3 ± 21.9

0.048

0.31 (0.11-0.84)

  1. SD standard deviation, HRCT high-resolution computed tomography, FVC forced vital capacity; FEV1: forced expiratory volume in 1 second; FEF25–75: forced expiratory flow from 25 % to 75 % of vital capacity. *χ2 or Fisher’s exact test (categorical variables); Wilcoxon’s rank-sum test (continuous variables). Significant differences are reported in bold. ** ORs from logistic regression models for an increment equal to 1 SD, calculated in patients with RP alone, after adjustment for age at diagnosis