Table 1 Characteristics of the main emollients
From: Consensus Conference on Clinical Management of pediatric Atopic Dermatitis
Product | Action | |
|---|---|---|
1st-generation emollients | Vaseline, paraffin oil, fatty alcohols, hydrophilic polymers (collagen, ac. hyaluronic acid, chitosan, polysaccharides gelling) | Hygroscopic and occlusive |
2nd-generation emollients | Glycerol, sorbitol, substitutes NMF (Natural Moisturizing Factor) derivatives of pyrrolidone carboxylic acid, urea (5–10 %), lactic acid, ammonium lactate | Restoring hydration and barrier function |
3rd-generation emollients | Physiological lipids: ceramides, cholesterol, polyunsaturated fatty acids | Barrier repair therapy |