Table 5 Classification of antihistamines (from AIFA repository 2015)
From: Consensus Conference on Clinical Management of pediatric Atopic Dermatitis
First-generation H1 antihistamines | Second-generation H1 antihistamines | Active metabolites of second-generation H1 antihistamines (third- generation H1 antihistamines) |
|---|---|---|
Alkilamines: Chlorpheniramine | Cetirizine | Levocetirizine |
Dimethindene | Loratadine | Decarboetoxiloratadine or Desloratadine |
Ethanolamines: Diphenhydramine | Ebastine | Norastemizole |
Ethylenediamines: Thonzylamine | Acrivastine | Fexofenadine |
Phenothiazines: Promethazine | Astemizole | |
Piperazines: Hydroxyzine | Terfenadine | |
Piperidines: Ciproeptadina | Azelastine | |
Oxatomide | Mizolastine | |
Intermediate degree of lipophilicity | Bilastine | |
Ketotifen | Rupatadine | |
Levocabastine |