Chen et al. 2008 [21] | Carrol et al. 2009 [23] | Sarafidis et al. 2010 [17] | Kevan et al. 2011 [22] | Miedema et al. 2011 [25] | Arzanian et al. 2011 [24] | Schlapbach et al. 2013 [18] | Mazzucchelli et al. 2013 [19] | Adly et al. 2014 [20] | |
---|---|---|---|---|---|---|---|---|---|
Was the spectrum of patients representative of the patients who will receive the test in practice? | − | − | + | − | − | + | + | − | − |
Were selection criteria clearly described? | − | + | + | + | − | + | − | − | + |
Is the reference standard likely to correctly classify the target condition? | + | + | + | + | + | + | + | + | + |
Is the time period between reference standard and index test short enough to be reasonably sure that the target condition did not change between the two tests? | + | + | + | + | + | + | + | + | + |
Did the whole sample or a random selection of the sample, receive verification using a reference standard of diagnosis? | + | + | + | + | ? | + | − | + | + |
Did patients receive the same reference standard regardless of the index test result? | + | + | + | + | + | + | + | + | + |
Was the reference standard independent of the index test (i.e. the index test did not form part of the reference standard)? | + | + | + | + | + | + | + | + | + |
Was the execution of the index test described in sufficient detail to permit replication of the test? | + | + | + | + | − | + | + | + | + |
Was the execution of the reference standard described in sufficient detail to permit its replication? | + | + | + | + | − | + | + | + | + |
Were the index test results interpreted without knowledge of the results of the reference standard? | + | + | + | + | + | + | + | + | + |
Were the reference standard results interpreted without knowledge of the results of the index test? | ? | ? | ? | ? | ? | ? | ? | ? | ? |
Were the same clinical data available when test results were interpreted as would be available when the test is used in practice? | + | + | + | + | + | + | + | + | + |
Were uninterpretable/intermediate test results reported? | + | + | + | + | + | ? | + | ? | ? |
Were withdrawals from the study explained? | + | + | + | + | + | ? | + | ? | ? |