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Table 2 Distribution of IL-6 genotypes in patients with febrile seizures (FS) and the control group

From: Interleukin-6 gene polymorphisms in Egyptian children with febrile seizures: a case–control study

Gene Polymorphism

Genotype

Patients n(%)

Controls n(%)

OR(95 % CI)

P

IL-6 (−174)

Sample size

100

100

  

GG

34 (34)

11(11)

4.17(1.86–9.49)

<0.01

GC

57(57)

73(73)

  

CC

9(9)

16 (16)

  

IL-6 (−572)

Sample size

98

100

  

GG

69(70.4)

65(65)

 

>0.05

GC

25(25.5)

33(33)

  

CC

4(4.1)

2(2)

  

IL-6 (−597)

Sample size

95

100

  

GG

62(65.3)

49(49)

1.96(1.06–3.63)

<0.05

GA

31(32.6)

48(48)

  

AA

2(2.1)

3(3)

  

Serum IL6 pg/ml

 

32.7 ± 5.9

10.5 ± 1.7

 

<0.01a

  1. Abbreviations: IL6 interleukin 6, FS febrile seizures, OR odds ratio, CI 95 % confidence interval
  2. Values in parentheses are percentages or data are presented as mean ± SD
  3. P value < 0.05 indicates a significant difference
  4. Chi-square test
  5. a (Student t-test)