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Table 4 Comparison of Genotype and Allele Frequency of IL-6 Polymorphisms between patients with simple febrile Seizure (SFS) and those with complex febrile seizures (CFS)

From: Interleukin-6 gene polymorphisms in Egyptian children with febrile seizures: a case–control study

Gene Polymorphism Genotype/Alleles SFS Group n(%) CFS Group n(%) P
IL-6 (−174) Sample size 63 37  
  GG 6(10) 3(8) >0.05
  GC 36(57) 21(57)  
  CC 21(33) 13(35)  
Alleles G 48(38) 27(36) >0.05
C 78(62) 47(64)  
IL-6 (−572) Sample size 61 37  
  GG 44(72) 25(68) >0.05
  GC 15(25) 10(27)  
  CC 2(3) 2(5)  
Alleles G 103(84) 60(81) >0.05
C 19(16) 14(19)  
IL-6 (−597) Sample size 59 36  
GG 32(54) 30(83) <0.01
GA 26(44) 5(14)  
AA 1(2) 1(3)  
Alleles G 90(76) 65(90) <0.05
A 28(24) 7(10)  
Serum IL6 pg/ml   31.5 ± 6.9 33.7 ± 5.6 >0.05a
  1. Abbreviations: IL6 interleukin 6, SFS Simple febrile seizures, CFS Complex febrile seizures
  2. P value < 0.05 indicates a significant difference. Chi-square test. a Student t-test