Table 4 Comparison of Genotype and Allele Frequency of IL-6 Polymorphisms between patients with simple febrile Seizure (SFS) and those with complex febrile seizures (CFS)
From: Interleukin-6 gene polymorphisms in Egyptian children with febrile seizures: a case–control study
Gene Polymorphism | Genotype/Alleles | SFS Group n(%) | CFS Group n(%) | P |
|---|---|---|---|---|
IL-6 (−174) | Sample size | 63 | 37 | |
GG | 6(10) | 3(8) | >0.05 | |
GC | 36(57) | 21(57) | ||
CC | 21(33) | 13(35) | ||
Alleles | G | 48(38) | 27(36) | >0.05 |
C | 78(62) | 47(64) | ||
IL-6 (−572) | Sample size | 61 | 37 | |
GG | 44(72) | 25(68) | >0.05 | |
GC | 15(25) | 10(27) | ||
CC | 2(3) | 2(5) | ||
Alleles | G | 103(84) | 60(81) | >0.05 |
C | 19(16) | 14(19) | ||
IL-6 (−597) | Sample size | 59 | 36 | |
GG | 32(54) | 30(83) | <0.01 | |
GA | 26(44) | 5(14) | ||
AA | 1(2) | 1(3) | ||
Alleles | G | 90(76) | 65(90) | <0.05 |
A | 28(24) | 7(10) | ||
Serum IL6 pg/ml | 31.5 ± 6.9 | 33.7 ± 5.6 | >0.05a |