Serum and CSF adiponectin, leptin, and interleukin 6 levels as adipocytokines in Egyptian children with febrile seizures: a cross-sectional study

Table 1 Baseline clinical and laboratory characteristics of FS patients and the control groups

	FS group	FC group	HC group	P
	(n = 100)	(n = 100)	(n = 100)
Age (months)	31 ± 7.5	33 ± 6.9	29 ± 8.3	>0.05
Gender (Male/female)^d	51/49	50/50	48/52	>0.05
BMI (kg/m²)	15.9 ± 1.2^a	16.3 ± 1.6^a	15.7 ± 1.8^a	>0.05
BT (C) on admission	38.9 ± 1.2	38.5 ± 1.3	_	>0.05
Type of infection ^d (bacterial/viral)	63/37	59/41	_	>0.05
Duration of fever ^d Before blood sample(<24 h/>24 h)	71/29	75/25	_	>0.05
Type of Febrile seizure : Simple/Complex	65/35	-	-
WBC (× 10⁹/L)	13.5 ± 4.3^a	14.1 ± 5.6^a	8.7 ± 2.6^b	<0.01
CRP (mg/dl)	38.4 ± 9.6^a	41.0 ± 11.5^a	3.8 ± 1.2^b	<0.01
Serum Adiponectin (ug/ml)	16.8 ± 3.7^a	18.3 ± 4.3^a	9.5 ± 2.2^b	<0.05
Serum Leptin (ng/ml)	0.9 ± 0.3^a	4.7 ± 1.2^b	1.8 ± 0.4^c	<0.01
Serum IL-6 (ng/ml)	43.7 ± 11.7^a	21.9 ± 4.5^b	6.5 ± 1.8^c	<0.01

Abbreviations: FS febrile seizures, FC febrile control, HC healthy control, BMI body mass index, BT body temperature, WBC white blood cell, CRP C-reactive protein, IL-6 Interleukin 6
Values are mean ± standard deviations or median (minimum- maximum)
The P value is for ANOVA. ^a, ^b and ^c on means refer to significant difference between means when ANOVA test refers to significances by multiple comparison analysis (aa, bb, cc = non-significant, ab, ac, bc = significant). ^dChi-square test

ISSN: 1824-7288