Adverse events
|
Clozapine
|
Olanzapine
|
Risperidone
|
Quetiapine
|
Ziprasidone
|
Aripiprazole
|
---|
Weight gain
|
++
|
++
|
+
|
+/−
|
+/−
|
+
|
Diabetes
|
++
|
++
|
+
|
+/−
|
+/−
|
+
|
Dyslipidemia
|
+
|
++
|
+
|
+/−
|
+/−
|
+/−
|
Extrapyramidal symptoms
|
−
|
+
|
++
|
+/−
|
++
|
+
|
Cardiac effect (mainly Qtc prologation)
|
+ a
|
+/−
|
+
|
+/−
|
++
|
+/−
|
Prolactin
|
−
|
+/−
|
+
|
−
|
+/−
|
− b
|
- Legend: ++ highest propensity to cause the index adverse event. + propensity to cause the index adverse event. +/− slight propensity to cause the index adverse event or inconsistent findings among papers. − neutral regarding the index adverse event. arisk for myocarditis. bpossible lowering effect