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Table 1 Summary of adverse events sorted by drugs

From: Update on the safety of second generation antipsychotics in youths: a call for collaboration among paediatricians and child psychiatrists

Adverse events Clozapine Olanzapine Risperidone Quetiapine Ziprasidone Aripiprazole
Weight gain ++ ++ + +/− +/− +
Diabetes ++ ++ + +/− +/− +
Dyslipidemia + ++ + +/− +/− +/−
Extrapyramidal symptoms − + ++ +/− ++ +
Cardiac effect (mainly Qtc prologation) + a +/− + +/− ++ +/−
Prolactin − +/− + − +/− − b
  1. Legend: ++ highest propensity to cause the index adverse event. + propensity to cause the index adverse event. +/− slight propensity to cause the index adverse event or inconsistent findings among papers. − neutral regarding the index adverse event. arisk for myocarditis. bpossible lowering effect
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Italian Journal of Pediatrics

ISSN: 1824-7288

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