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Table 3 SNPs genotype distribution in Current Wheezers (CUWH) Vs Controls (NWNA) and HDL-C levels

From: Shared genetic variants between serum levels of high-density lipoprotein cholesterol and wheezing in a cohort of children from Cyprus

SNP (genotype)

NWNA (n, %)

CUWH (n, %)

χ 2

p value

p trend

HDL mg/dl (mean, 95 % CI)

F

p value

p trend

ADRB2 rs1800888

         

 CC

609 (95 %)

175 (97.8 %)

   

53.3 (52.3–54.2)

   

 CT

32 (5.0 %)

4 (2.2 %)

2.535

0.076b

-

57.2 (51.7–62.8)

2.840

0.092c

-

TNFa rs3093664

         

 AA

500 (79.6)

134 (76.1)

   

53.3 (52.2–54.3)

   

 AG

102 (16.2)

40 (22.7)

   

51.7 (49.4–54.1)

   

 GG

26 (4.1)

2 (1.1)

7.047

0.03a

0.912

65.3 (59.2–71.4)

11.787

>0.001c

0.028

PRKCA rs9892651

         

 TT

230 (37.0)

52 (30.2)

   

55.2 (53.4–56.9)

   

 CT

302 (48,6)

87 (50.6)

   

52.7 (51.4–54.1)

   

 CC

89 (14.3)

33 (19.2)

3.921

0.141a

0.048

52.2 (50.0–54.5)

3.179

0.042c

0.020

  1. a χ 2 test (asymptomatic 2- sided significance)
  2. bFischer Exact test (exact 1-sided significance)
  3. cComparisons of means (One way ANOVA)