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Table 3 SNPs genotype distribution in Current Wheezers (CUWH) Vs Controls (NWNA) and HDL-C levels

From: Shared genetic variants between serum levels of high-density lipoprotein cholesterol and wheezing in a cohort of children from Cyprus

SNP (genotype) NWNA (n, %) CUWH (n, %) χ 2 p value p trend HDL mg/dl (mean, 95 % CI) F p value p trend
ADRB2 rs1800888          
 CC 609 (95 %) 175 (97.8 %)     53.3 (52.3–54.2)    
 CT 32 (5.0 %) 4 (2.2 %) 2.535 0.076b - 57.2 (51.7–62.8) 2.840 0.092c -
TNFa rs3093664          
 AA 500 (79.6) 134 (76.1)     53.3 (52.2–54.3)    
 AG 102 (16.2) 40 (22.7)     51.7 (49.4–54.1)    
 GG 26 (4.1) 2 (1.1) 7.047 0.03a 0.912 65.3 (59.2–71.4) 11.787 >0.001c 0.028
PRKCA rs9892651          
 TT 230 (37.0) 52 (30.2)     55.2 (53.4–56.9)    
 CT 302 (48,6) 87 (50.6)     52.7 (51.4–54.1)    
 CC 89 (14.3) 33 (19.2) 3.921 0.141a 0.048 52.2 (50.0–54.5) 3.179 0.042c 0.020
  1. a χ 2 test (asymptomatic 2- sided significance)
  2. bFischer Exact test (exact 1-sided significance)
  3. cComparisons of means (One way ANOVA)
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Italian Journal of Pediatrics

ISSN: 1824-7288

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