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Table 3 Clinical measures of the whole sample at T0 and T1, and number of children who improved in the different domains

From: Can biological components predict short-term evolution in Autism Spectrum Disorders? A proof-of-concept study

  M ± SD
  T0 T1 p
ADOS composite 13.63 ± 3.67 10.85 ± 4.10 <0.0001
A 4.72 ± 1.74 3.39 ± 1.75 <0.001
B 8.91 ± 2.27 7.46 ± 2.79 <0.0001
C 2.86 ± 1.11 2.39 ± 1.28 <0.01
D 3.71 ± 1.56 3.17 ± 1.75 <0.01
CSS 5.34 ± 1.44 4.51 ± 1.46 <0.0001
DQ 0.64 ± 0.14 0.66 ± 0.15 <0.01
  DQ sub-quotients:
Cognitive abilities 0.72 ± 0.19 0.77 ± 0.21 <0.0001
Expressive language 0.44 ± 0.16 0.47 ± 0.19 <0.05
Receptive language 0.52 ± 0.18 0.57 ± 0.23 <0.01
Fine motor abilities 0.73 ± 0.15 0.73 ± 0.17 =0.915
Gross motor abilities 0.78 ± 0.16 0.78 ± 0.17 =0.799
Visual motor imitation 0.68 ± 0.15 0.68 ± 0.14 =0.964
  Number (Percent)
Improvement in both ADOS classification and DQ level 14 (15.2 %)
Improvement in ADOS classification 34 (37.0 %)
Improvement in DQ level 31 (33.7)%
Improvement in cognitive abilities 47 (51.1 %)
Improvement in expressive language 40 (43.5 %)
Improvement in receptive language 35 (38.1 %)
Improvement in fine-motor abilities 30 (32.6 %)
Improvement in gross motor abilities 35 (38.1 %)
Improvement in visual-motor imitation 29 (31.5 %)
  1. N = 92; ADOS Autism Diagnostic Observation Schedule, CSS Calibrate Severity Score, DQ Developmental Quotient, Statistically significant results are in bold