Skip to main content

Table 5 Clinical measures of the evolution for the four subgroups at T0 and T1

From: Can biological components predict short-term evolution in Autism Spectrum Disorders? A proof-of-concept study

  CS (N = 24) ID (N = 31) ND (N = 9) SB (N = 28)
  T0 T1 p T0 T1 p T0 T1 p T0 T1 p
ADOS composite 13.79 ± 3.61 11.58 ± 3.82 <0.05 13.84 ± 3.83 11.23 ± 4.01 <0.0001 16.00 ± 3.64 14.11 ± 3.55 =0.120 12.50 ± 3.28 8.75 ± 4.11 <0.001
A 4.88 ± 1.85 3.75 ± 1.65 <0.05 4.90 ± 1.68 3.35 ± 1.58 <0.0001 5.44 ± 2.01 4.78 ± 1.48 =0.373 4.14 ± 1.53 2.68 ± 1.83 <0.001
B 8.92 ± 2.19 7.83 ± 2.58 =0.083 8.94 ± 2.41 7.87 ± 2.78 <0.01 10.56 ± 1.74 9.33 ± 2.29 =0.055 8.36 ± 2.18 6.07 ± 2.64 <0.01
C 2.67 ± 1.05 2.29 ± 1.27 =0.266 3.13 ± 1.09 2.48 ± 1.31 <0.01 3.44 ± 0.88 3.22 ± 1.30 =0.622 2.54 ± 1.14 2.11 ± 1.20 =0.089
D 3.92 ± 1.44 2.88 ± 1.62 <0.05 3.55 ± 1.67 3.52 ± 1.57 =0.903 4.44 ± 1.88 4.33 ± 2.06 =0.346 3.46 ± 1.40 2.68 ± 1.79 <0.01
CSS 5.58 ± 1.61 4.75 ± 1.36 <0.05 5.23 ± 1.63 4.68 ± 1.42 <0.05 5.56 ± 1.01 5.12 ± 1.05 =0.220 5.18 ± 1.19 3.93 ± 1.56 <0.01
Global DQ 0.61 ± 0.12 0.63 ± 0.11 =0.070 0.62 ± 0.13 0.65 ± 0.16 =0.190 0.50 ± 0.09 0.50 ± 0.07 =0.907 0.73 ± 0.12 0.76 ± 0.14 =0.060
Cognitive abilities 0.67 ± 0.17 0.73 ± 0.16 <0.05 0.71 ± 0.20 0.76 ± 0.20 =0.087 0.55 ± 0.10 0.55 ± 0.14 =0.855 0.82 ± 0.16 0.90 ± 0.19 =0.055
Expressive language 0.38 ± 0.08 0.42 ± 0.14 =0.163 0.41 ± 0.12 0.45 ± 0.18 =0.179 0.36 ± 0.08 0.29 ± 0.08 <0.05 0.53 ± 0.23 0.59 ± 0.21 <0.05
Receptive language 0.46 ± 0.15 0.48 ± 0.12 =0.342 0.49 ± 0.14 0.53 ± 0.21 =0.156 0.42 ± 0.08 0.38 ± 0.10 =0.110 0.64 ± 0.20 0.73 ± 0.26 <0.05
Fine motor abilities 0.70 ± 0.16 0.74 ± 0.14 =0.200 0.71 ± 0.14 0.71 ± 0.17 =0.733 0.59 ± 0.12 0.54 ± 0.07 =0.097 0.81 ± 0.12 0.81 ± 0.16 =0.995
Gross motor abilities 0.76 ± 0.18 0.81 ± 0.19 =0.332 0.77 ± 0.15 0.76 ± 0.16 =0.629 0.60 ± 0.14 0.62 ± 0.13 =0.721 0.86 ± 0.13 0.82 ± 0.17 =0.112
Visual motor imitation 0.66 ± 0.16 0.65 ± 0.10 =0.783 0.68 ± 0.14 0.70 ± 0.15 =0.448 0.55 ± 0.14 0.55 ± 0.09 =0.914 0.75 ± 0.11 0.73 ± 0.13 =0.586
  1. CS Circadian and sensory dysfunction subgroup, ID Immune dysfunction subgroup, ND Neurodevelopmental delay subgroup, SB Stereotypic behaviour subgroup, ADOS Autism Diagnostic Observation Schedule, CSS Calibrate Severity Score, DQ Developmental Quotient. Statistically significant results are in bold