|
CS (N = 24)
|
ID (N = 31)
|
ND (N = 9)
|
SB (N = 28)
|
---|
|
T0
|
T1
|
p
|
T0
|
T1
|
p
|
T0
|
T1
|
p
|
T0
|
T1
|
p
|
---|
ADOS composite
|
13.79 ± 3.61
|
11.58 ± 3.82
|
<0.05
|
13.84 ± 3.83
|
11.23 ± 4.01
|
<0.0001
|
16.00 ± 3.64
|
14.11 ± 3.55
|
=0.120
|
12.50 ± 3.28
|
8.75 ± 4.11
|
<0.001
|
A
|
4.88 ± 1.85
|
3.75 ± 1.65
|
<0.05
|
4.90 ± 1.68
|
3.35 ± 1.58
|
<0.0001
|
5.44 ± 2.01
|
4.78 ± 1.48
|
=0.373
|
4.14 ± 1.53
|
2.68 ± 1.83
|
<0.001
|
B
|
8.92 ± 2.19
|
7.83 ± 2.58
|
=0.083
|
8.94 ± 2.41
|
7.87 ± 2.78
|
<0.01
|
10.56 ± 1.74
|
9.33 ± 2.29
|
=0.055
|
8.36 ± 2.18
|
6.07 ± 2.64
|
<0.01
|
C
|
2.67 ± 1.05
|
2.29 ± 1.27
|
=0.266
|
3.13 ± 1.09
|
2.48 ± 1.31
|
<0.01
|
3.44 ± 0.88
|
3.22 ± 1.30
|
=0.622
|
2.54 ± 1.14
|
2.11 ± 1.20
|
=0.089
|
D
|
3.92 ± 1.44
|
2.88 ± 1.62
|
<0.05
|
3.55 ± 1.67
|
3.52 ± 1.57
|
=0.903
|
4.44 ± 1.88
|
4.33 ± 2.06
|
=0.346
|
3.46 ± 1.40
|
2.68 ± 1.79
|
<0.01
|
CSS
|
5.58 ± 1.61
|
4.75 ± 1.36
|
<0.05
|
5.23 ± 1.63
|
4.68 ± 1.42
|
<0.05
|
5.56 ± 1.01
|
5.12 ± 1.05
|
=0.220
|
5.18 ± 1.19
|
3.93 ± 1.56
|
<0.01
|
Global DQ
|
0.61 ± 0.12
|
0.63 ± 0.11
|
=0.070
|
0.62 ± 0.13
|
0.65 ± 0.16
|
=0.190
|
0.50 ± 0.09
|
0.50 ± 0.07
|
=0.907
|
0.73 ± 0.12
|
0.76 ± 0.14
|
=0.060
|
Cognitive abilities
|
0.67 ± 0.17
|
0.73 ± 0.16
|
<0.05
|
0.71 ± 0.20
|
0.76 ± 0.20
|
=0.087
|
0.55 ± 0.10
|
0.55 ± 0.14
|
=0.855
|
0.82 ± 0.16
|
0.90 ± 0.19
|
=0.055
|
Expressive language
|
0.38 ± 0.08
|
0.42 ± 0.14
|
=0.163
|
0.41 ± 0.12
|
0.45 ± 0.18
|
=0.179
|
0.36 ± 0.08
|
0.29 ± 0.08
|
<0.05
|
0.53 ± 0.23
|
0.59 ± 0.21
|
<0.05
|
Receptive language
|
0.46 ± 0.15
|
0.48 ± 0.12
|
=0.342
|
0.49 ± 0.14
|
0.53 ± 0.21
|
=0.156
|
0.42 ± 0.08
|
0.38 ± 0.10
|
=0.110
|
0.64 ± 0.20
|
0.73 ± 0.26
|
<0.05
|
Fine motor abilities
|
0.70 ± 0.16
|
0.74 ± 0.14
|
=0.200
|
0.71 ± 0.14
|
0.71 ± 0.17
|
=0.733
|
0.59 ± 0.12
|
0.54 ± 0.07
|
=0.097
|
0.81 ± 0.12
|
0.81 ± 0.16
|
=0.995
|
Gross motor abilities
|
0.76 ± 0.18
|
0.81 ± 0.19
|
=0.332
|
0.77 ± 0.15
|
0.76 ± 0.16
|
=0.629
|
0.60 ± 0.14
|
0.62 ± 0.13
|
=0.721
|
0.86 ± 0.13
|
0.82 ± 0.17
|
=0.112
|
Visual motor imitation
|
0.66 ± 0.16
|
0.65 ± 0.10
|
=0.783
|
0.68 ± 0.14
|
0.70 ± 0.15
|
=0.448
|
0.55 ± 0.14
|
0.55 ± 0.09
|
=0.914
|
0.75 ± 0.11
|
0.73 ± 0.13
|
=0.586
|
-
CS Circadian and sensory dysfunction subgroup, ID Immune dysfunction subgroup, ND Neurodevelopmental delay subgroup, SB Stereotypic behaviour subgroup, ADOS Autism Diagnostic Observation Schedule, CSS Calibrate Severity Score, DQ Developmental Quotient. Statistically significant results are in bold