Table 1 Principal features at diagnosis in the 2 groups of patients with GNAS gene mutations and GNAS locus altered methylation
|  | N° Subjects | Sex: F/M | Age | Ca (mEq/l) | P (mg/dl) | PTH (pg/ml) | TSH (μU/ml) |
|---|---|---|---|---|---|---|---|
Gene mutation | 46 | 29/17 | 4.8 (0.1–23.4) | 4.3 (2.25–6.7) | 6.8 (4–12.2) | 308 (15.6–1200) | 7.8 (1.6–22.1) |
Locus altered methylation | 28 | 16/12 | 10.5 (0.5–65) | 3.6 (1.9–9.2) | 6.9 (3.6–10.5) | 358 (128–1532) | 5 (3.36–8.95) |