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Table 3 The haplotypic association of the four SNPs of the DARS gene with VSD

From: Association of DARS gene polymorphisms with the risk of isolated ventricular septal defects in the Chinese Han population

Haplotypea

Case (%)

Control (%)

OR (95% CI)

P

GGA

712(42.33)

2551(43.19)

1.00(referent)

 

GGG

562(33.41)

1893(32.05)

1.06(0.94-1.21)

3.35 × 10-1

AAG

94(5.59)

289(4.89)

1.17(0.91-1.49)

2.24 × 10-1

GAG

90(5.35)

248(4.20)

1.30(1.01-1.68)

4.30 × 10 -2

AGA

140(8.32)

681(11.53)

0.74(0.60-0.90)

3.00 × 10 -3

Others

84(4.99)

244(4.13)

1.23(0.95-1.60)

1.15 × 10-1

  1. aSNP order: rs2164331, rs6738266, rs309143