Table 3 Indications for allergen-specific immunotherapy (AIT) for pediatric allergic rhinitis, conjunctivitis with/without asthma

AIT should be considered for patients with evidence of specific IgE sensitization towards one or few clinically relevant allergen(s).

The decision to start AIT depends on various factors including:

 • Children’s (and caregivers) preference and acceptability

 • Adherence to treatment

 • Severity of symptoms and pharmacotherapy requirements

 • Efficacy of avoidance measures (e.g. house dust mites, pollens)

 • Asthma and co-existent rhinitis

Potential indications:

 • Possible prevention of new sensitizations in mono-sensitized patients

 • IgE-associated food allergy

 • Extrinsic atopic dermatitis