Fig. 1
From: Metabolic progression to clinical phenotype in classic Fabry disease
a, Familial pedigree of two brothers (“x” and “y”) with classic Fabry disease (details in text). Patient “0” was diagnosed with end-stage renal disease due to classic Fabry disease at 35 years of age. b, Globotriaosylsphingosine (LysoGb3) assessed on dried blood spot (DBS) in two brothers (“x” and “y”) at different metabolic and clinical stages of classic Fabry disease