Table 2 Distribution of IL-10 genotypes, alleles and serum IL-10 levels in patients with Juvenile idiopathic arthritis (JIA) and control group
Genotype | Â | Patient group | Control group | OR (95% CI) | P | ||
|---|---|---|---|---|---|---|---|
n (100) | % | n (100) | % | ||||
IL-10 (-1082) | AA | 23 | (23) | 10 | (10) | 2.7 (1.1–6.4) | <0.05 |
AG | 69 | (69) | 73 | (73) | |||
GG | 8 | (8) | 17 | (17) | |||
Alleles | |||||||
|  | A | 115 | (57.5) | 93 | (46.5) | 1.5 (1.03–2.3) | < 0.05 |
G | 85 | (42.5) | 107 | (53.5) | 0.6 (0.4–0.9) | ||
−819/-592 | TT/AA | 23 | (23) | 19 | (19) |  | > 0.05 |
CT/CA | 65 | (65) | 71 | (71) | |||
CC/CC | 12 | (12) | 10 | (10) | |||
Alleles | |||||||
| Â | T/A | 111 | (55.5) | 109 | (54.5) | Â | > 0.05 |
C/C | 89 | (44.5) | 91 | (45.5) | |||
Serum IL10 (pg/ml) |  | 7.4 ± 1.5 | 5.6 ± 1.3 |  | > 0.05a | ||