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Table 2 Distribution of IL-10 genotypes, alleles and serum IL-10 levels in patients with Juvenile idiopathic arthritis (JIA) and control group

From: Association of IL-10 gene polymorphisms and susceptibility to Juvenile Idiopathic Arthritis in Egyptian children and adolescents: a case-control study

Genotype   Patient group Control group OR (95% CI) P
n (100) % n (100) %
IL-10 (-1082) AA 23 (23) 10 (10) 2.7 (1.1–6.4) <0.05
AG 69 (69) 73 (73)
GG 8 (8) 17 (17)
Alleles
  A 115 (57.5) 93 (46.5) 1.5 (1.03–2.3) < 0.05
G 85 (42.5) 107 (53.5) 0.6 (0.4–0.9)
−819/-592 TT/AA 23 (23) 19 (19)   > 0.05
CT/CA 65 (65) 71 (71)
CC/CC 12 (12) 10 (10)
Alleles
  T/A 111 (55.5) 109 (54.5)   > 0.05
C/C 89 (44.5) 91 (45.5)
Serum IL10 (pg/ml)   7.4 ± 1.5 5.6 ± 1.3   > 0.05a
  1. Abbreviations: IL-10 interleukin-10, OR odds ratio, CI 95% confidence interval
  2. Values in parentheses are percentages or data are presented as mean ± SD
  3. P value < 0.05 indicates a significant difference. Chi-square test. a Student t-test