Table 2 Most commonly reported active substances in Group A
From: Pattern of drug use among preterm neonates: results from an Italian neonatal intensive care unit
Active substance | Exposure (N = 68) | % (tot. 100) | Courses | Courses/exposure | Duration per course, d (average) |
|---|---|---|---|---|---|
Ampicillina | 66 | 97.1 | 66 | - | - |
Amikacina | 66 | 97.1 | 76 | 1.2 | 6 |
Caffeine | 65 | 95.6 | 76 | 1.2 | 35 |
Fluconazole | 63 | 92.6 | 83 | 1.3 | 25 |
Calcitriol | 60 | 88.2 | 74 | 1.2 | 39 |
Furosemidea | 49 | 72.1 | 106 | 2.2 | 6 |
Fentanyl | 45 | 66.2 | 84 | 1.9 | 8 |
Hydrochlorothiazide | 34 | 50.0 | 50 | 1.5 | 31 |
Spironolactone | 34 | 50.0 | 51 | 1.5 | 30 |
Piperacillin and enzyme inhibitora | 32 | 47.1 | 43 | 1.3 | 9 |
Lung surfactant - natural phospholipids | 31 | 45.6 | 34 | 1.1 | 3 |
Dopamine | 30 | 44.1 | 38 | 1.3 | 9 |
Metronidazole | 27 | 39.7 | 30 | 1.1 | 11 |
Calcium folinate | 26 | 38.2 | 27 | 1.0 | 35 |
Tobramycin | 26 | 38.2 | 35 | 1.3 | 6 |
Folic acid | 25 | 36.8 | 28 | 1.1 | 31 |
Dobutamine | 25 | 36.8 | 32 | 1.6 | 6 |
Immunoglobulins, normal human, for intravascular administration | 24 | 35.3 | 30 | 1.3 | 3 |
Vancomycina | 24 | 35.3 | 37 | 1.3 | 9 |
Heparinoids for topical use | 23 | 33.8 | 30 | 1.5 | 4 |
Ibuprofena | 22 | 32.4 | 22 | - | - |
Ranitidine | 21 | 30.9 | 22 | 1.1 | 24 |
Filgrastim | 21 | 30.9 | 26 | 1.2 | 1 |
Clarithromycin | 20 | 29.4 | 24 | 1.2 | 13 |
Dexamethasone | 19 | 27.9 | 36 | 1.9 | 12 |
Calcifediol | 18 | 26.5 | 22 | 1.2 | 32 |
Atropine | 17 | 25.0 | 19 | 1.1 | 1 |
Albumin | 16 | 23.5 | 23 | 1.4 | 1 |
Betamethasone | 14 | 20.6 | 17 | 1.2 | 6 |
Erythromycin ethylsuccinate | 13 | 19.1 | 13 | - | - |
Lorazepam | 12 | 17.6 | 23 | 1.9 | 1 |
Doxapram | 12 | 17.6 | 15 | 1.3 | 12 |
Phytomenadione | 11 | 16.2 | 13 | 1.2 | 17 |
Oxacillin | 11 | 16.2 | 13 | 1.2 | 8 |
Paracetamol (Acetaminophen)a | 11 | 16.2 | 19 | 1.7 | 6 |
Beclometasone | 11 | 16.2 | 13 | 1.1 | 11 |
Ferrous sulfate | 10 | 14.7 | 11 | 1.1 | 16 |
Amphotericin Ba | 9 | 13.2 | 10 | 1.6 | 18 |
Midazolam | 9 | 13.2 | 14 | 1.1 | 10 |
Insulin (human) | 9 | 13.2 | 10 | 1.6 | 3 |
Antacids with sodium bicarbonate | 7 | 10.3 | 11 | 1.3 | 4 |
Glyceryl trinitrate | 7 | 10.3 | 7 | - | - |
Phenobarbital | 6 | 8.8 | 6 | - | - |
Ceftazidime | 6 | 8.8 | 9 | 1.5 | 14 |
Mupirocin | 6 | 8.8 | 8 | 1.3 | 4 |
Morphine | 5 | 7.4 | 7 | 1.4 | 20 |
Hydrocortisone | 4 | 5.9 | 5 | 1.3 | 8 |
Calcium levofolinate | 4 | 5.9 | 4 | - | - |
Erythromycin | 4 | 5.9 | 6 | 1.5 | 14 |
Naloxone | 4 | 5.9 | 4 | - | - |
Epinephrine | 3 | 4.4 | 3 | - | - |
Indometacina | 3 | 4.4 | 3 | - | - |
Epoprostenol | 3 | 4.4 | 6 | 2.0 | 5 |
Linezolid | 3 | 4.4 | 3 | - | - |