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Table 4 Biochemical tests

From: The Italian Society for Pediatric Nephrology (SINePe) consensus document on the management of nephrotic syndrome in children: Part I - Diagnosis and treatment of the first episode and the first relapse

Tests

Blood

Urine

Mandatory

▪ Complete Blood Count (CBC)

▪ BUN, creatinine

▪ Electrolytes (including ionized calcium)

▪ Serum total protein, albumin

▪ Cholesterol, triglycerides

▪ CRP

▪ Coagulation (including ATIII)

▪ Immunoglobulins

▪ Complement (C3, C4)

▪ Urinalysis (early morning sample)

▪ 24-h proteinuria or Proteinuria/creatininuria (uP/uCr)

Additional

▪ Auto-immune markers (ANA, DS-DNA, ENA, ANCA)

▪ Thyroid function

▪ Infections (HBV, HCV, HIV, ParvoB19, CMV, EBV, pneumococcus, salmonella, treponema, mycoplasma…)

▪ Urine sodium