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Table 1 Demographic characteristics

From: Efficacy and safety of early supplementation with 800 IU of vitamin D in very preterm infants followed by underlying levels of vitamin D at birth

Characteristics All patients
(n = 52)
Cord 25(OH)D concentrations <10 ng/mL (n = 20) Cord 25(OH)D concentrations ≥10 ng/mL (n = 29)
Maternal age, years 34.3 ± 3.4 32.4 ± 3.1 33.8 ± 4.0
GDM 6 (12%) 5 (25%) 1 (3%)*
Preeclampsia 4 (8%) 0 (0%) 3 (10%)
Antenatal steroid 44 (85%) 19 (95%) 22 (79%)
Histological Chorioamnionitis 33 (64%) 11 (55%) 21 (72%)
Completed college 38 (73) 13 (65%) 24 (83%)
Birth during vitamin D synthesizing period 30 (58%) 7 (35%) 20 (69%)
Gestational age (weeks) 27.1 ± 2.5 27.5 ± 2.5 26.8 ± 2.6
Small gestational age 8 (15%) 2 (10%) 5 (17%)
Birth weight (g) 971.2 ± 252.4 1045.5 ± 271.8 933.5 ± 203.6
Birth length (cm) 34.1 ± 3.5 34.3 ± 3.4 34.1 ± 3.6
Birth head circumference (cm) 24.6 ± 2.2 24.8 ± 2.3 24.5 ± 2.2
Male sex 26 (50%) 7 (35%) 16 (55%)
Cesarean section 40 (77%) 18 (90%) 20 (71%)
Apgar score at 5 min 5.1 ± 1.5 5.3 ± 1.7 4.9 ± 1.3
RDS 47 (90%) 17 (85%) 27 (96%)
PDA 35 (67%) 15 (79%) 19 (66%)
NEC 3 (6%) 0 (0%) 2 (7%)
Culture-proven sepsis 17 (33%) 5 (26%) 11 (38%)
BPD (≥ moderate) 25 (48%) 7 (37%) 16 (55%)
ROP (≥ stage 2) 24 (46%) 8 (40%) 14 (50%)
IVH (≥ grade 2) 6 (12%) 4 (20%) 2 (7%)
Breast milk with/without formula 38 (73%) 13 (65%) 22 (76%)
Exclusively fortified breast milk 13 (25%) 5 (25%) 8 (28%)
Ventilation days (d) 24.1 ± 18.4 20.9 ± 18.1 20.9 ± 18.1
Hospital days (d) 85.5 ± 33.2 77.6 ± 24.8 86.6 ± 28.3
TPN days (d) 47.1 ± 32.5 37.2 ± 22.7 47.2 ± 22.4
  1. Data are presented as n (%), median (range), or mean ± SD
  2. GDM gestational diabetes mellitus, RDS respiratory distress syndrome, PDA patent ductus arteriosus, NEC necrotizing enterocolitis, BPD bronchopulmonary dysplasia, ROP retinopathy of prematurity, IVH intraventricular hemorrhage, TPN total parenteral nutrition
  3. * P = 0.035 for the difference between cord 25(OH)D concentrations < 10 ng/mL vs. ≥ 10 ng/mL
  4. P = 0.023 for the difference between cord 25(OH)D concentrations < 10 ng/mL vs. ≥ 10 ng/mL