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Table 1 Demographic characteristics

From: Efficacy and safety of early supplementation with 800 IU of vitamin D in very preterm infants followed by underlying levels of vitamin D at birth

Characteristics

All patients

(n = 52)

Cord 25(OH)D concentrations <10 ng/mL (n = 20)

Cord 25(OH)D concentrations ≥10 ng/mL (n = 29)

Maternal age, years

34.3 ± 3.4

32.4 ± 3.1

33.8 ± 4.0

GDM

6 (12%)

5 (25%)

1 (3%)*

Preeclampsia

4 (8%)

0 (0%)

3 (10%)

Antenatal steroid

44 (85%)

19 (95%)

22 (79%)

Histological Chorioamnionitis

33 (64%)

11 (55%)

21 (72%)

Completed college

38 (73)

13 (65%)

24 (83%)

Birth during vitamin D synthesizing period

30 (58%)

7 (35%)

20 (69%)

Gestational age (weeks)

27.1 ± 2.5

27.5 ± 2.5

26.8 ± 2.6

Small gestational age

8 (15%)

2 (10%)

5 (17%)

Birth weight (g)

971.2 ± 252.4

1045.5 ± 271.8

933.5 ± 203.6

Birth length (cm)

34.1 ± 3.5

34.3 ± 3.4

34.1 ± 3.6

Birth head circumference (cm)

24.6 ± 2.2

24.8 ± 2.3

24.5 ± 2.2

Male sex

26 (50%)

7 (35%)

16 (55%)

Cesarean section

40 (77%)

18 (90%)

20 (71%)

Apgar score at 5 min

5.1 ± 1.5

5.3 ± 1.7

4.9 ± 1.3

RDS

47 (90%)

17 (85%)

27 (96%)

PDA

35 (67%)

15 (79%)

19 (66%)

NEC

3 (6%)

0 (0%)

2 (7%)

Culture-proven sepsis

17 (33%)

5 (26%)

11 (38%)

BPD (≥ moderate)

25 (48%)

7 (37%)

16 (55%)

ROP (≥ stage 2)

24 (46%)

8 (40%)

14 (50%)

IVH (≥ grade 2)

6 (12%)

4 (20%)

2 (7%)

Breast milk with/without formula

38 (73%)

13 (65%)

22 (76%)

Exclusively fortified breast milk

13 (25%)

5 (25%)

8 (28%)

Ventilation days (d)

24.1 ± 18.4

20.9 ± 18.1

20.9 ± 18.1

Hospital days (d)

85.5 ± 33.2

77.6 ± 24.8

86.6 ± 28.3

TPN days (d)

47.1 ± 32.5

37.2 ± 22.7

47.2 ± 22.4

  1. Data are presented as n (%), median (range), or mean ± SD
  2. GDM gestational diabetes mellitus, RDS respiratory distress syndrome, PDA patent ductus arteriosus, NEC necrotizing enterocolitis, BPD bronchopulmonary dysplasia, ROP retinopathy of prematurity, IVH intraventricular hemorrhage, TPN total parenteral nutrition
  3. * P = 0.035 for the difference between cord 25(OH)D concentrations < 10 ng/mL vs. ≥ 10 ng/mL
  4. P = 0.023 for the difference between cord 25(OH)D concentrations < 10 ng/mL vs. ≥ 10 ng/mL