Effects of inhaled hypertonic (7%) saline on lung function test in preschool children with cystic fibrosis: results of a crossover, randomized clinical trial

Table 2 Lung function measured at time 0 (T0), after 4 (T4) and 16 weeks (T16) in the 12 patients who inhaled hypertonic saline

	T0	T4	T16	T0vsT4	T0vsT16
FVC (l)	1.42 ± 0.39	1.45 ± 0.39	1.49 ± 0.42	ns	p = 0.02
FVC % pred	89.2 ± 8.3	90.7 ± 7.7	91.9 ± 8.3	p = 0.048	p = 0.02
FEV₁ (l)	1.25 ± 0.35	1.16 ± 0.23	1.25 ± 0.38	ns	ns
FEV₁% pred	87.1 ± 9.5	85.7 ± 8.3	89.6 ± 9.6	ns	p = 0.09
FEF_25-75 (l/s)	1.43 ± 0.22	1.42 ± 0.36	1.47 ± 0.39	ns	ns
FEF_25-75% pred	77.0 ± 9.7	74.8 ± 5.6	77.1 ± 5.9	ns	ns
Rint exp. kPa(l/s)	1.25 ± 0.19	1.30 ± 0.22	1.24 ± 0.19	ns	ns
Rint insp. kPa(l/s)	1.26 ± 0.18	1.28 ± 0.16	1.21 ± 0.20	ns	ns

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