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Table 2 Lung function measured at time 0 (T0), after 4 (T4) and 16 weeks (T16) in the 12 patients who inhaled hypertonic saline

From: Effects of inhaled hypertonic (7%) saline on lung function test in preschool children with cystic fibrosis: results of a crossover, randomized clinical trial

  T0 T4 T16 T0vsT4 T0vsT16
FVC (l) 1.42 ± 0.39 1.45 ± 0.39 1.49 ± 0.42 ns p = 0.02
FVC % pred 89.2 ± 8.3 90.7 ± 7.7 91.9 ± 8.3 p = 0.048 p = 0.02
FEV1 (l) 1.25 ± 0.35 1.16 ± 0.23 1.25 ± 0.38 ns ns
FEV1% pred 87.1 ± 9.5 85.7 ± 8.3 89.6 ± 9.6 ns p = 0.09
FEF25-75 (l/s) 1.43 ± 0.22 1.42 ± 0.36 1.47 ± 0.39 ns ns
FEF25-75% pred 77.0 ± 9.7 74.8 ± 5.6 77.1 ± 5.9 ns ns
Rint exp. kPa(l/s) 1.25 ± 0.19 1.30 ± 0.22 1.24 ± 0.19 ns ns
Rint insp. kPa(l/s) 1.26 ± 0.18 1.28 ± 0.16 1.21 ± 0.20 ns ns
  1. Data were expressed as mean values ± SD