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Table 3 Lung function measured at time zero (T0), after 4 (T4) and 16 weeks (T16) in the 12 children who inhaled normal saline

From: Effects of inhaled hypertonic (7%) saline on lung function test in preschool children with cystic fibrosis: results of a crossover, randomized clinical trial

  T0 T4 T16 T0vsT4 T0vsT16
FVC (l) 1.31 ± 0.36 1.23 ± 0.28 1.29 ± 0.35 ns ns
FVC % pred. 89.7 ± 8.3 85.4 ± 9.3 87.9 ± 9.1 p = 0.01 ns
FEV1 (1) 1.25 ± 0.25 1.07 ± 0.20 1.14 ± 0.24 p < 0.0001 p < 0.0001
FEV1% pred 90.7 ± 8.6 85.1 ± 7.9 87.8 ± 6.7 p < 0.0001 ns
FEF25-75 (l/s) 1.51 ± 0.39 1.30 ± 0.24 1.40 ± 0.30 p = 0.012 ns
FEF25-75% pred 78.7 ± 6.1 65.9 ± 9.7 72.1 ± 9.4 p = 0.001 p = 0.019
Rint exp. kPa (l/s) 1.23 ± 0.17 1.50 ± 0.33 1.29 ± 0.19 p = 0.02 ns
Rint insp. kPa (l/s) 1.19 ± 0.19 1.37 ± 0.49 1.26 ± 0.21 ns ns
  1. Data were expressed as mean values ± SD