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Table 1 Drug treatments for pneumonia in children as suggested by Esposito S et al. (Esposito et al., 2012), revised

From: Monitoring adherence to guidelines of antibiotic use in pediatric pneumonia: the MAREA study

Antibiotic choice

Dose and route of administration

Total duration of treatment

First choice

 Amoxicillin

50–90 mg/kg/d (max 3.000 mg) in 2–3 doses. Oral

5–7 days

 Ampicillin

100 mg/kg/d (max 12.000 mg) in 3–4 doses. iv

5–7 days

 Clarithromycin

15 mg/kg/d (max 1.000 mg) in 2 divided doses. Oral

14 days

 Clarithromycin

4–8 mg/kg/day in 2 divided doses. iv

14 days

 Azithromycin

10 mg/kg/d (max 500 mg) in 1 dose. Oral

3 days

1 dose of 10 mg/kg/d and then 5 mg/kg/d. oral

4 days

Second choice

 Amoxicillin/clavulanate

amoxicillin component: 50–90 mg/kg/d (max 3.000 mg) in 2 doses. Oral

5–7 days

 Ampicillin/sulbactam

150 mg/kg/d (max 9.000 mg) in 3 doses. iv

 Cefuroxime axetil

20–30 mg/kg/d in 2 divided doses. Oral

 Benzylpenicillin iv

200.000 units/kg/d in 4–6 doses. iv

 Ceftriaxone

80–100 mg/kg (max 2.000 mg) once a day. iv

 Cefotaxime

100–150 mg/kg/d in 3 divided doses. iv

 Cefaclor

20–40 mg/kg once a day. Oral

 Cefpodoxime proxetil

8 mg/kg once a day. Oral

  1. Combination therapy with a beta-lactam drug and a macrolide can be considered in more severe cases or when an atypical bacterial infection is suspected