LEVEL OF EVIDENCE (LE) |
---|
I Evidence obtained from several RCTs and/or reviews of RCT |
II Evidence obtained from one RT adequately designed |
III Evidence obtained from non randomized cohort studies with case/control or their methanalysis |
IV Evidence obtained from case/control retrospective studies or their methanalysis |
V Evidence obtained from series of cases without control group |
VI Evidences obtained from experts advice, from consensus conferences, etc. |
GRADE OF RECOMMENDATION (GR) |
A Surgical or diagnostic procedures are strongly recommended because they are sustained by high level scientific evidence, even if not necessarily of type I or II |
B It is doubtful that the procedure must be always recommended but it must be carefully considered |
C There exists an element of uncertainty both in favor and against the recommendation |
D The procedure is not recommended |
E The procedure is strongly ill-advised |