Skip to main content

Table 1 Prediction score models of IVIG resistance in KD patients

From: A comparison of efficacy of six prediction models for intravenous immunoglobulin resistance in Kawasaki disease

Prediction models

Nation

Year

Enrolled patients, n

Patients with IVIG resistance, n

Sensitivity, %

Specificity, %

Risk factors

Points

Predicted risk (score)

Kobayashi

Japan

2006

528

148

86

68

Age ≤ 12 mo

1

Low risk (0–2)

High risk (≥ 3)

Illness days ≤4 d

2

CRP ≥ 10 mg/dL

1

AST ≥ 100 IU/L

2

PLT ≤ 300 ×  109/L

1

Na ≤ 133 mmol/L

2

N% ≥ 80%

2

Egami

Japan

2006

320

41

78

76

Age ≤ 6 mo

1

Low risk (0–2)

High risk (≥ 3)

Illness days ≤4 d

1

CRP ≥ 8 mg/dl

1

ALT ≥80 IU/L

2

PLT < 300 × 109/L

1

Kawamura

Japan

2016

405

85

71

69

NLR ≥ 3.83

PLR ≥ 150

-

-

Sano

Japan

2007

112

22

77

86

CRP ≥ 7.0 mg

1

Low risk (0–1)

High risk (≥ 2)

TB ≥ 0.9 mg/dl

1

AST ≥ 200 IU/L

1

Formosa

Taiwan

2015

248

29

86.2

81.3

lymphadenopathy

1

Low risk (0–2)

N% ≥ 60%

2

High risk (≥ 3)

ALB < 35 g/L

1

 

Ours

China

2016

910

46

71.4

76.0

Age <  6 months

2

Low risk (0–2)

High risk (≥ 3)

Rash

1

Edema of extremities

1

N% ≥80%

1

ALB < 35 g/L

2

  1. CRP c-reactive protein, PLT platelet count, Na serum sodium, N% percentage of neutrophils, ALB serum albumin, ALT alanine aminotransferase, AST aspartate aminotransferase, TB total bilirubin, NLR neutrophil-to-lymphocyte ratio, PLR platelet-to-lymphocyte ratio