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Table 4 Historical, clinical and laboratory data of the subgroups considering as risk factors prior antibiotic treatment, age less than 2 years and fever higher than 38.5 °C

From: Acute mastoiditis in an Italian pediatric tertiary medical center: a 15 – year retrospective study

  Age ≤ 2 yr.
(N 42)
Age > 2 yr.
(N 105)
P value Prior antibiotic
(N 86)
No prior antibiotic
(N 61)
P value Fever
(N 109)
No fever
(N 38)
P value
Mean Age (years) 5.5 ± 3.7 3.8 ± 3.1 < 0.005 4.1 ± 3.1 6.9 ± 4.1 < 0.0001
Median Age (years) 4.8
(0.4–13.2)
2.7
(0.3–13.5)
< 0.005 3.3
(0.4–12-6)
6.3
(0.3–13-5)
< 0.0001
Hospitalization (days) 9 ± 3.4 8.5 ± 7.8 NS 8.7 ± 5.2 8.5 ± .8.7 NS 8.8 ± 7.1 8.1 ± 5.8 NS
Prior antibiotic treatment (days) 1.5 ± 3.1 2.7 ± 2.9 < 0.05   2.3 ± 3.1 2.6 ± .2.9 NS
Symptom duration (days) 4.2 ± 3.9 5.3 ± 4.2 NS 6 ± 4.4 3.7 ± 3.2 < 0.0001 5.2 ± 4.3 4.4 ± 3.4 NS
WBC (10^3/mmc) 18,440 ± 6115 14,370 ± 4550 < 0.0001 14,550±
5090
16,920±
5450
< 0.01 16,250 ± 5405 13,470 ± 4680 < 0.01
CPR (mg/dl) 9.5 ± 7.7 6.8 ± 11 NS 6.1 ± 5.9 9.6 ± 14.1 NS 9.2 ± 11.3 2.8 ± 3.4 < 0.0001
Antibiotic treatment (days) 8.9 ± 3.4 8.2 ± 4.5 NS 9.2 ± 4.7 7.3 ± 3.2 < 0.005 8.6 ± 3.6 8 ± 5.2 NS
Antibiotic treatment (mg/kg/die) 75 ± 17 66 ± 20 < 0.01 69 ± 20 69 ± 19 NS 72 ± 19 59 ± 19 < 0.001
Complications (%, n° pts) 14 (6) 8 (8) NS 65 (9) 35 (5) NS 10 (11) 8 (3) NS
Fever (%, n° pts) 86 (36) 69 (73) < 0.05 74 (64) 82 (50) NS
Othalgia (%, n° pts) 48 (20) 88 (93) < 0.0001 78 (67) 75 (46) NS 73 (83) 91 (30) < 0.05
Othorrea (%, n° pts) 26 (11) 25 (26) NS 30 (26) 18 (11) NS 26 (28) 24 (9) NS
Protrusion of auricle (%, n° pts) 76 (32) 60 (63) NS 62 (53) 69 (42) NS 67 (76) 59 (19) NS
Retroauricular swelling (%, n° pts) 78 (33) 54 (56) < 0.01 54 (63) 57 (35) NS 65 (74) 47 (15) NS
Retroauricular erythema (%, n° pts) 74 (31) 72 (75) NS 70 (60) 75 (46) NS 73 (83) 72 (23) NS
Retroauricular pain (%, n° pts) 28 (12) 60 (62) < 0.001 46 (54) 28 (46) NS 46 (52) 69 (22) < 0.05
  1. Historical, clinical and laboratory data of the subgroups considering as risk factors prior antibiotic treatment, age less than 2 years and fever higher than 38.5 °C. NS = not significance