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Table 1 Gaps in the evidence of AIT for prevention

From: The future outlook on allergen immunotherapy in children: 2018 and beyond

Major gaps in the evidence of prevention

❖ Long-term effectiveness of AIT in preventing asthma in children with AR due to grass pollen

❖ Effectiveness of AIT in preventing asthma in children with AR due to house dust mites

❖ Identification of the optimal age for introduction of AIT for prevention

❖ Identification of the optimal duration of AIT for prevention

❖ Identification of the optimal product, administration form, dose and schedule of AIT for prevention

❖ Evaluation of healthy economics of AIT for prevention

❖ Evaluation of acceptability of AIT for prevention in different patient groups (age, pattern of sensitization and clinical characteristics) and healthy individuals

❖ Identification of the most suitable candidates

❖ “Precision preventive medicine” algorithms