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Table 4 Indication for the oral glucose tolerance test in children and adolescents with overweight or obesity

From: Diagnosis, treatment and prevention of pediatric obesity: consensus position statement of the Italian Society for Pediatric Endocrinology and Diabetology and the Italian Society of Pediatrics

Children with fasting plasma glucose ≥100 mg/dl or HbA1c ≥5.7–6.4% (39–46 mmol/mol) Adolescents (> 10 years of age) or at onset of puberty with overweight (BMI > 85th percentile) and at least one of the following risk factors:  - Family history of T2DM in first- or second-degree relatives;  - Race/ethnicity (African American, Latino, Native American, Asian American, or Pacific Islander);  - Signs or conditions associated with insulin resistance (hypertension, dyslipidaemia, polycystic ovary syndrome, acanthosis nigricans, or small for gestational age at birth)  - Maternal history of diabetes or gestational diabetes during the child’s gestation  - Non alcholic liver disease  - TG/HDL-Cholesterol ≥2.2  - Fasting plasma glucose ≥86 mg/dl  - TG > 100 mg/dl and fasting plasma glucose > 80 mg/dl