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Table 2 Late effects of ALL treatment

From: Late effects in survivors of childhood acute lymphoblastic leukemia in the context of selected gene polymorphisms

Late effect

n

%

Endocrine – hyperthyroidism, hypothyroidism, hyperprolactinemia, testosterone deficiency, growth hormone deficiency, obesity, infertility

27

22

Hepatitis B or C

23

18

Psychological – dyslexia, impairment of cognitive function and memory

12

10

Neurological – recurrent headache, epilepsy

7

6

Gynecological – menstruation disorders

6

5

Psychiatric - depression, phobia, anorexia

4

3

Second neoplasm – meningioma (2 cases), cervical cancer, haeeamangioma of the liver

4

3

Musculoskeletal – bone and muscle pain, vertebral column pain, scoliosis, osteoporosis

9

7

Allergy

3

2

Dermatological – psoriasis, eczema

3

2

Nephrological – nephrolithiasis, nephropathy

3

2

Gastrointestinallogical – cholelithiasis, gastritis

3

2

Pulmonary – asthma, recurrent pneumonia

2

1.6

Ocular – diplopia

1

0.8

Cardiovascular – hypertension, hypotension

2

1,6

Ear, nose throat – hearing impairment

1

0.8

Immunological - immunodeficiency

1

0.8