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Table 1 Clinical and laboratory data of the two children with drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome

From: Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome in two young children: the importance of an early diagnosis

 

ADMISSION

DRESS SYNDROME ONSET

DIAGNOSIS OF DRESS SYNDROME

DISCHARGE

Case 1

Case 2

Case 1

Case 2

Case 1

Case 2

Case 1

Case 2

Laboratory data (normal value)

Day 1

Day 1

Day 26

Day 14

Day 30

Day 18

Day 40

Day 28

WBC (4800–12,100/μL)

16,650

5600

14,980

8320

26,280

12,140

12,760

7820

Lymphocytes (1500–16,500//μL)

3120

2040

3800

4500

6710

4200

3200

3320

Eosinophils (100–500//μL)

200

220

2330

30

5010

2940

480

440

CRP (< 0.5 mg/dL)

19.59

0.59

3.60

10.31

6.1

3.19

0.03

0.14

AST-ALT (5–36 U/L and 5–29 U/L)

23–22

31–28

34–27

402–62

55–132

1560–311

25–45

36–60

LDH (120–300 U/L)

198

276

779

3637

805

10,880

238

300

PT-aPTT (0.94–1.22 and 0.86–1.20)

Not performed

Not performed

1.28–1.10

Not performed

1.31–1.06

1.23–1.94

0.98–0.95

0.96–1.03

D-dimer (< 230 ng/mL)

Not performed

Not performed

1815

Not performed

2000

68,384

120

230

  1. WBC white blood cells, CRP C-reactive protein, AST aspartate aminotransferase, ALT alanine aminotransferase, LDH lactate dehydrogenase, PT prothrombin time, aPTT activated partial thromboplastin time