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Table 2 Results of the RegiSCAR scoring system used to diagnose drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome in two children

From: Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome in two young children: the importance of an early diagnosis

Items

Patient 1

Score: patient 1

Patient 2

Score: patient 2

Fever ≥ 38.5 °C

Yes

0

Yes

0

Enlarged lymph nodes

Yes

1

Yes

1

Eosinophils a

Yes

2

Yes

2

Atypical lymphocytes

No

0

No

0

Skin rash > 50% of body surface area

Yes

1

Yes

1

Skin rash suggesting DRESS

Yes

1

Yes

1

Skin biopsy suggesting DRESS

Yes

1

Not applicable

0

Liver involvement

Yes

1

Yes

1

Resolution ≥ 15 days

No

-1

No

-1

Evaluation other potential causes b

Negative

1

Negative

1

Total score

 

7

 

6

  1. a: eosinophils 0.7–1.49 × 103/mmc = 1; ≥1.5 × 103/mmc = 2
  2. b: include ANA, blood culture, serology for HVA/ HVB/ HVC, Chlamydia/ Mycoplasma pneumonia, other serology/PCR. None positive and ≥ 3 of the above negative = 1
  3. Legend: Final score < 2: no case, final score 2–3: possible case, final score 4–5: probable case, and final score > 5: definite case