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Table 1 Level (class) based on study design, defined as follows

From: Kawasaki disease: guidelines of the Italian Society of Pediatrics, part I - definition, epidemiology, etiopathogenesis, clinical expression and management of the acute phase

class I meta-analyses or systematic reviews from randomized controlled trials
class II single randomized controlled trials
class III nonrandomized controlled trials
class IV retrospective case-control studies
class V number of cases without control group
class VI opinions of committees of experts and authorities