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Table 6 Main laboratory abnormalities in patients with Kawasaki disease

From: Kawasaki disease: guidelines of the Italian Society of Pediatrics, part I - definition, epidemiology, etiopathogenesis, clinical expression and management of the acute phase

BLOOD CELL COUNT

white blood cells

↑, maximal elevation of polymorphonuclear cells

↓ rarely

red blood cells

↓, normal mean corpuscular volume

platelets

↑, typically in the II and III week, normalization in 4–8 weeks

if ↓ suspect disseminated intravascular dissemination

INFLAMMATORY PARAMETERS

erythro-sedimentation rate (ESR)

↑, slow normalization

C-reactive protein (CRP)

↑, fast normalization

LIVER FUNCTION TESTS

transaminases

↑

bilirubinemia

↑

gamma-glutamyl transpeptidase

↑

albuminemia

more severe and prolonged illness if ↓

OTHER LABORATORY TESTS

urine

white blood cells > 10/high field powered

cerebrospinal fluid

aseptic meningitis (presence of mononuclear cells, normal glucose/proteins)

synovial fluid

purulent-appearing fluid, white blood cells 125.000–300.000/mm3, normal glucose level