Fig. 1From: New treatments for the mucopolysaccharidoses: from pathophysiology to therapyThe pathology and the clinical manifestations of mucopolysaccharidoses are only in part the direct consequences of the storage of substrates. A new vision of lysosomal disease pathophysiology suggests that secondary and tertiary events, such as activation of cellular pathways, significantly contribute to the occurrence of tissue damage and clinical manifestationsBack to article page