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Table 1 PROS: PIK3CA-Related Overgrowth Spectrum

From: Clinical pitfalls in the diagnosis of segmental overgrowth syndromes: a child with the c.2740G > A mutation in PIK3CA gene

MCAP (megalencephaly-capillary malformations syndrome)
DMEG (dysplastic megalencephaly)
CLOVES (Congenital Lipomatous Overgrowth, Vascular Malformations, Epidermal Nevi, Scoliosis/Skeletal and Spinal syndrome)
HHML (hemihyperplasia-multiple lipomatosis)
Fibroadipose hyperplasia or Overgrowth (FAO)
Klippel-Trenaunay Syndrome
Fibroadipose Infiltrating Lipomatosis, Seborrheic keratosis (SK), Benign lichenoid keratosis (BLK), Epidermal nevi (EN)