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Fig. 2 | Italian Journal of Pediatrics

Fig. 2

From: Evidence that a primary anti-viral stimulation of the immune response by OM-85 reduces susceptibility to a secondary respiratory bacterial infection in mice

Fig. 2

Sublethal influenza virus infection of BALB/c mice. a Experimental overview: mice were treated orally with OM-85 or control solution (BLANC) daily for 10 days and then infected by the intranasal administration of a sublethal dose (100 PFU) of influenza virus strain PR8. b Survival scheme of mice treated with OM-85 or BLANC and subsequently infected with sublethal dose of influenza virus. The percentage of mice surviving the infection is on the ordinate and the days after the infection is on the abscissa. c, d and e Morbidity of OM-85 or BLANC treated mice and then infected with a sublethal dose of influenza virus. The clinical score, body temperature (expressed in Celsius degrees), and body weight loss (expressed as percentage of the original weight) are on the ordinate and the days after the influenza virus infection on the abscissa. Data are representative of 3 experiments, with 5–10 mice per time point

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