Table 2 Asthma standard therapy and FEV1 before omalizumab (T0) and after 1 month (T1), 3 months (T3), 6 months (T6), 12 months (T12)
From: Omalizumab in children with severe allergic disease: a case series
Patient | Age | Omalizumab | Duration of treatment (weeks) | T0 | T1 | T3 | T6 | T12 | First Aid Access | Hospitalization | ACT | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Maintenance Treatment | FEV1, % | Maintenance Treatment | FEV1, % | Maintenance Treatment | FEV1, % | Maintenance Treatment | FEV1, % | Maintenance Treatment | FEV1, % | |||||||
1 | 11 | 375 mg every 2 weeks | 78 | Fluticasone 1000 mcg/die LABA 100 mcg/die LTRA 10 mg/die | 70 | Fluticasone 1000 mcg/die LABA 100 mcg/die LTRA 10 mg/die | 70 | Fluticasone 500 mcg/die LABA 100 mcg/die | 75 | Fluticasone 250 mcg/die | 86 | Suspended | 99 | 1 | 1 | 20 |
2 | 15 | 450 mg every 4 weeks | 96 | Fluticasone 1000 mcg/die LABA 100 mcg/die LTRA 10 mg/die | 70 | Fluticasone 500 mcg/die LABA 100 mcg/die LTRA 10 mg/die | 70 | Fluticasone 200 mcg/die LABA 100 mcg/die | 73 | Fluticasone 200 mcg/die | 76 | Suspended | 101 | 1 | 1 | 25 |
3 | 10 | 300 mg every 4 weeks | 16 | Fluticasone 500 mcg/die LABA 100 mcg/die | 73 | Fluticasone 500 mcg/die LABA 100 mcg/die | 73 | Fluticasone 200 mcg/die LABA 100 mcg/die | 75 | Fluticasone 200 mcg/die | 80 | Suspended | 101 | 1 | 1 | 20 |
4 | 9 | 150 mg every 4 weeks | 104 | Fluticasone 500 mcg/die LABA 100 mcg/die LTRA 10 mg/die | 61 | Fluticasone 500 mcg/die LABA 100 mcg/die LTRA 10 mg/die | 67 | Fluticasone 500 mcg/die LABA 100 mcg/die | 73 | Fluticasone 200 mcg/die LABA 100 mcg/die | 79 | Fluticasone 200 mcg/die | 85 | 2 | 2 | 20 |
5 | 7 | 75 mg every 4 weeks | 16 | – | / | – | / | OIT | / | OIT | / | Milk desensitiz-ation | / | / | / | NO |
6 | 14 | 450 mg every 4 weeks | 48 | Fluticasone 1000 mcg/die LABA 100 mcg/die | 73 | Fluticasone 1000 mcg/die LABA 100 mcg/die | 73 | Fluticasone 500 mcg/die LABA 100 mcg/die | 75 | Fluticasone 250 mcg/die | 80 | Suspended | 100 | 2 | 2 | 20 |
7 | 8 | 75 mg every 4 weeks | 16 | – | / | – | / | OIT | / | OIT | / | Milk desensitiz-ation | / | / | / | NO |
8 | 10 | 300 mg every 2 weeks | 48 | Fluticasone 500 mcg/die LABA 100 mcg/die | 76 | Fluticasone 500 mcg/die LABA 100 mcg/die | 76 | Fluticasone 250 mcg/die LABA 100 mcg/die | 76 | Fluticasone 250 mcg/die | 80 | Fluticasone 200 mcg/die | 89 | 2 | 2 | 20 |