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Table 2 Asthma standard therapy and FEV1 before omalizumab (T0) and after 1 month (T1), 3 months (T3), 6 months (T6), 12 months (T12)

From: Omalizumab in children with severe allergic disease: a case series

Patient Age Omalizumab Duration of treatment (weeks) T0 T1 T3 T6 T12 First Aid Access Hospitalization ACT
Maintenance Treatment FEV1, % Maintenance Treatment FEV1, % Maintenance Treatment FEV1, % Maintenance Treatment FEV1, % Maintenance Treatment FEV1, %
1 11 375 mg every 2 weeks 78 Fluticasone 1000 mcg/die
LABA 100 mcg/die
LTRA 10 mg/die
70 Fluticasone 1000 mcg/die
LABA 100 mcg/die
LTRA 10 mg/die
70 Fluticasone 500 mcg/die
LABA 100 mcg/die
75 Fluticasone 250 mcg/die 86 Suspended 99 1 1 20
2 15 450 mg every 4 weeks 96 Fluticasone 1000 mcg/die
LABA 100 mcg/die
LTRA 10 mg/die
70 Fluticasone 500 mcg/die
LABA 100 mcg/die
LTRA 10 mg/die
70 Fluticasone 200 mcg/die
LABA 100 mcg/die
73 Fluticasone 200 mcg/die 76 Suspended 101 1 1 25
3 10 300 mg every 4 weeks 16 Fluticasone 500 mcg/die
LABA 100 mcg/die
73 Fluticasone 500 mcg/die
LABA 100 mcg/die
73 Fluticasone 200 mcg/die
LABA 100 mcg/die
75 Fluticasone 200 mcg/die 80 Suspended 101 1 1 20
4 9 150 mg every 4 weeks 104 Fluticasone 500 mcg/die
LABA 100 mcg/die
LTRA 10 mg/die
61 Fluticasone 500 mcg/die
LABA 100 mcg/die
LTRA 10 mg/die
67 Fluticasone 500 mcg/die
LABA 100 mcg/die
73 Fluticasone 200 mcg/die
LABA 100 mcg/die
79 Fluticasone 200 mcg/die 85 2 2 20
5 7 75 mg every 4 weeks 16 / / OIT / OIT / Milk desensitiz-ation / / / NO
6 14 450 mg every 4 weeks 48 Fluticasone 1000 mcg/die
LABA 100 mcg/die
73 Fluticasone 1000 mcg/die
LABA 100 mcg/die
73 Fluticasone 500 mcg/die
LABA 100 mcg/die
75 Fluticasone 250 mcg/die 80 Suspended 100 2 2 20
7 8 75 mg every 4 weeks 16 / / OIT / OIT / Milk desensitiz-ation / / / NO
8 10 300 mg every 2 weeks 48 Fluticasone 500 mcg/die
LABA 100 mcg/die
76 Fluticasone 500 mcg/die
LABA 100 mcg/die
76 Fluticasone 250 mcg/die
LABA 100 mcg/die
76 Fluticasone 250 mcg/die 80 Fluticasone 200 mcg/die 89 2 2 20
  1. Abbreviations: ACT asthma control test, FEV1 forced expiratory volume in 1 s, LABA long acting β2 agonist, OIT oral immunotherapy