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Table 1 Laboratory tests

From: Not only Alagille syndrome. Syndromic paucity of interlobular bile ducts secondary to HNF1β deficiency: a case report and literature review

Tests

Reference range

5 weeks

2 months

6.5 months

9 months

11 months

14 months

16 months

18 months

Liver function tests

         

Bilirubin total (mg/dL)

< 1

11.95

15.5

4.3

1.6

1.3

2.2

2.5

2.8

Conjugated bilirubin (mg/dL)

< 0.2

6.68

13.5

4.1

1.5

1.2

2.1

2.2

2.4

AST (IU/L)

< 50

210

276

86

75

92

189

135

87

ALT (IU/L)

< 40

320

349

47

63

90

332

177

77

GGT (IU/L)

< 50

221

1631

986

872

1129

1629

969

657

bile acids (mg/dL)

< 10

150

264

117

304

253

132

Albumin (g/dL)

3.6–5.2

3.7

3.3

3.7

4

4

4.2

4.2

Cholesterol (mg/dL)

< 200

361

270

349

256

HDL cholesterol (mg/dL)

> 40

-

-

-

-

-

133

101

-

LDL cholesterol (mg/dL)

< 90

-

-

-

-

-

179

131

-

Triglycerides (mg/dL)

< 105

135

138

119

187

120

78

Kidney function tests

Serum creatinine (mg/dL)

0.18–0.33

0.58

0.5

0.51

0.5

0.47

0.46

0.50

eGFR* (ml/min/1.73m2)

 

37

55

56

62

66

67

66

Uric acid (mg/dL)

< 6

3.6

3.8

3.2

2.5

2.8

PrU/CrU** (mg/mg)

< 0.2

1.7

0

0

0

0

0.2

0

Hemoglobin (g/dL)

10.5–13.5

9

10.7

9.9

13.6

11.1

11.6

10.8

  1. *estimated glomerular filtration rate (Schwartz’s eGFR = 0.413 x length/sCr)
  2. **proteinuria/creatininuria index