Fig. 1

– Inherited ichthyosis clinical features. 9-year-old boy affected by autosomal recessive congenital ichthyosis (ARCI) showing generalized skin involvement with dark, large, and adherent scales (a), while a 3-year-old child also affected with ARCI presents diffuse skin erythema (erythroderma), in addition to whitish scales (b); the child shown in (a) also has bilateral ectropion (upper and lower lid eversion), a common and severe disease complication (c); plantar keratoderma in a 17-year-old ARCI patient (d)