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Table 3 Genotype and allele frequencies of the MTHFD1 G1958A polymorphism in case and control groups

From: Association of neural tube defects with maternal alterations and genetic polymorphisms in one-carbon metabolic pathway

Genotype

Case(N = 61)

Control(N = 61)

χ2 values

OR

95%CI

P values

GG

23(37.7)

37(60.7)

 

1

  

GA

34(55.7)

21(34.4)

6.331

2.600

1.227~5.529

0.012*

AA

4(6.6)

3(4.9)

 

2.145

0.440~10.464

0.427**

G

80(65.6)

95(77.9)

 

1

  

A

42(34.4)

27(22.1)

4.547

1.847

1.047~3.259

0.033*

  1. Note: *P value< 0.05 indicates that the genotype and allele distributions of MTHFD1 G1958A polymorphism exhibit a significant difference between case and control groups
  2. **P value are calculated using Fisher’s exact test
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Italian Journal of Pediatrics

ISSN: 1824-7288

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