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Table 4 Genotype and allele frequencies of the MTHFR C677T polymorphism in case and control groups

From: Association of neural tube defects with maternal alterations and genetic polymorphisms in one-carbon metabolic pathway

Genotype

Case(N = 61)

Control(N = 61)

χ2values

OR

95%CI

P values

CC

5(8.2)

15(24.6)

 

1

  

CT

30(49.2)

27(44.3)

4.559

3.333

1.068~10.400

0.033*

TT

26(42.6)

19(31.1)

5.963

4.105

1.271~13.258

0.015*

C

40(32.8)

57(46.7)

 

1

  

T

82(67.2)

65(53.3)

4.945

1.798

1.070~3.021

0.026*

  1. Note: *P value< 0.05 indicates that the genotype and allele distributions of MTHFR C677T polymorphism exhibit a significant difference between case and control groups
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Italian Journal of Pediatrics

ISSN: 1824-7288

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