Skip to main content

Table 2 Descriptive statistics for analyzed measurable traits in the studied patients by study arm and phase of the study

From: Vitamin D inhibits pro-inflammatory cytokines in the airways of cystic fibrosis patients infected by Pseudomonas aeruginosa- pilot study

Analyzed trait

Study arm

Phase of the study

Statistical parameter

Level of statistical significance (p-value)

Ma

SD†

95% CIb

Min. – max.

Age (years)

  

16,50

4,38

14,32-18,68

10–24

a

b

Phosphor (mmol/L)

Calcitriol 0,5 mcg

Before treatment

1,48

0,27

1,35-1,61

1,03-1,93

= 0,021

= 0,359

After treatment

1,35

0,20

1,26-1,45

1,04-1,70

Cholecalciferol 1000 IU

Before treatment

1,53

0,23

1,42-1,64

1,05-1,87

= 0,080

After treatment

1,44

0,18

1,35-1,54

1,21-1,82

Calcium (mg/dL)

Calcitriol 0,5 mcg

Before treatment

3,50

2,60

2,28-4,72

2,22-9,80

= 0,001

= 0,041

After treatment

4,35

3,35

2,78-5,92

2,22-10,52

Cholecalciferol 1000 IU

Before treatment

2,81

1,62

2,03-3,59

2,22-9,48

= 0,185

After treatment

3,62

2,58

2,41-4,83

2,15-9,80

Parathormone (pg/ml)

Calcitriol 0,5 mcg

Before treatment

35,64

17,61

27,40-43,88

16,99-89,12

= 0,019

= 0,208

After treatment

29,36

13,08

23,23-35,48

9,76-72,73

Cholecalciferol 1000 IU

Before treatment

38,30

13,62

31,92-44,67

17,56-72,73

= 0,334

After treatment

34,76

16,07

26,77-42,75

17,07-89,12

Urinary calcium/creatinine ratio (mg/dL: mg/dL)

Calcitriol 0,5 mcg

Before treatment

0,262

0,195

0,168-0,356

0,030-0,800

= 0,966

= 0,232

After treatment

0,239

0,201

0,143-0,336

0,040-0,800

Cholecalciferol 1000 IU

Before treatment

0,252

0,138

0,188-0,317

0,020-0,500

= 0,050

After treatment

0,195

0,138

0,124-0,266

0,020-0,500

25-OH D (ng/mL)

Calcitriol 0,5 mcg

Before treatment

24,19

8,43

20,24-28,13

5,20-40,00

= 0,125

= 0,064

After treatment

28,19

9,75

23,63-32,76

8,10-42,90

Cholecalciferol 1000 IU

Before treatment

24,13

9,86

19,52-28,74

9,40-48,30

= 0,567

After treatment

24,97

10,86

19,89-30,06

8,00-49,00

IL-17A in the exhaled air (pg/mL)

Calcitriol 0,5 mcg

Before treatment

0,475

0,515

0,234-0,717

0,050-1910

= 0,008

= 0,044

After treatment

0,384

0,429

0,184-0,585

0,070-1800

Cholecalciferol 1000 IU

Before treatment

0,450

0,395

0,265-0,635

0,050-1910

= 0,074

After treatment

0,290

0,195

0,199-0,382

0,070-0,710

IL-23 in the exhaled air (pg/mL)

Calcitriol 0,5 mcg

Before treatment

9,39

6,40

6,39-12,38

2,12-30,72

= 0,086

= 0,399

After treatment

7,46

5,13

5,06-9,86

1,03-20,37

Cholecalciferol 1000 IU

Before treatment

8,90

4,07

7,00-10,80

3,04-20,72

= 0,001

After treatment

7,33

3,88

5,51-9,15

1,03–18,20

  1. (aM – mean, †SD – standard deviation, bCI – confidence interval. Mixed-effects regression models with robust standard errors, due to the small sample size, were performed: a – considering repeated measurements in the two separate studies; b – considering the above-mentioned repeated measurements, along with differences between the two studies and intra-subject correlation, on grounds of the cross-over study design. All statistical calculations were controlled for the studied patients’ age and sex)
Back to article page

Italian Journal of Pediatrics

ISSN: 1824-7288

Contact us