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Table 3 Factors associated with antibiotic use: results of univariate and multivariate logistic analysis

From: Prevalence of antibiotic use in a tertiary care hospital in Italy, 2008–2016

 

N. total patients

N. patients with at least 1 prescription

%

Unadjusted OR (CI 95%)

P-value

Adjusted ORa (CI 95%)

P-value

Year

 2008

379

159

42.0

1

 

1

 

 2009

267

123

46.1

1.2 (0.9–1.6)

0.3

1.2 (0.9–1.6)

0.3

 2010

320

170

53.1

1.6 (1.2–2.1)

0.003

1.5 (1.1–2.1)

0.005

 2011

320

160

50.0

1.4 (1.0–1.9)

0.03

1.4 (1.0–1.9)

0.03

 2012

353

190

53.8

1.6 (1.2–2.2)

0.001

1.6 (1.2–2.1)

0.002

 2013

344

174

50.6

1.4 (1.1–1.9)

0.02

1.4 (1.0–1.8)

0.03

 2014

333

165

49.5

1.4 (1.0–1.8)

0.04

1.3 (1.0–1.8)

0.05

 2015

368

189

51.4

1.5 (1.1–2.0)

0.01

1.4 (1.0–1.9)

0.02

 2016

331

186

56.2

1.8 (1.3–2.4)

< 0.001

1.8 (1.3–2.4)

< 0.001

Sex

 Female

1352

656

48.5

1

 

1

 

 Male

1663

860

51.7

1.1 (0.9–1.3)

0.08

1.1 (1.0–1.3)

0.06

Age

 ≤2 months

507

233

45.9

1

 

1

 

 3–11 months

497

218

43.9

0.9 (0.7–1.2)

0.5

1.0 (0.8–1.3)

0.8

 1–5 years

760

386

50.8

1.2 (1.0–1.5)

0.09

1.5 (1.2–1.9)

0.001

 6–11 years

776

425

54.8

1.4 (1.1–1.8)

0.002

1.7 (1.4–2.2)

< 0.001

 ≥ 12 years

469

250

53.3

1.3 (1.0–1.7)

0.02

1.6 (1.3–2.1)

< 0.001

 Missing

6

4

 

 

Length of hospital stay (days)

 ≤7

1480

696

47.0

1

 

1

 

 08–30

962

540

56.1

1.4 (1.2–1.7)

< 0.001

1.4 (1.2–1.7)

< 0.001

 > 30

571

279

48.9

1.1 (0.9–1.3)

0.5

1.0 (0.8–1.2)

1.0

 Missing

2

1

 

 

Ward

 Medical

1031

463

44.9

1

 

1

 

 Surgical

810

410

50.6

1.3 (1.0–1.5)

0.02

1.3 (1.1–1.6)

0.01

 Medical subspecialty unit

861

449

52.1

1.3 (1.1–1.6)

0.002

1.3 (1.1–1.6)

0.003

 Intensive care

313

194

62.0

2.0 (1.5–2.6)

< 0.001

2.4 (1.8–3.2)

< 0.001

  1. aORs were adjusted for sex, year, age, length of hospital stay, ward type