Table 2 Clinical, hormonal and metabolic characteristics according to retinopathy
From: The impact of IGF-I, puberty and obesity on early retinopathy in children: a cross-sectional study
Group A (normal) | Group B (retinopathy) | P | |
|---|---|---|---|
Males/females (n°) | 110/146 | 5/4 | 0.56 |
Prepubertal/Pubertal (n°) | 43/213 | 0/9 | 0.36 |
Age (years) | 13.04 ± 1.9 | 12.9 ± 1.02 | 0.81 |
BMI SDS (Italy) | 2.17 ± 0.5 | 2.39 ± 0.7 | 0.23 |
Waist circumference (cm) | 99.46 ± 10.85 | 107.78 ± 15.83 | 0.027 |
Waist/height ratio | 0.62 ± 0.05 | 0.66 ± 0.07 | 0.04 |
Systolic blood pressure (mmHg) | 120.5 ± 10.1 | 121.8 ± 10.8 | 0.72 |
Diastolic blood pressure (mmHg) | 67.1 ± 9.4 | 67.7 ± 10.9 | 0.83 |
Fasting glucose (mg/dl) | 85.5 ± 7.3 | 86.3 ± 7.2 | 0.73 |
Fasting insulin (mU/L) | 25.67 ± 17.4 | 23.2 ± 10.7 | 0.69 |
Fasting C peptide (ng/ml) | 2.07 ± 0.7 | 2.01 ± 0.75 | 0.84 |
HOMA-IR | 5.5 ± 3.9 | 5.05 ± 2.6 | 0.43 |
QUICKI | 0.31 ± 0.02 | 0.30 ± 0.01 | 0.58 |
AUC glucose (mg/min/ml) | 13,950,12 ± 2070.7 | 13,901 ± 1616,8 | 0.94 |
AUC insulin (microUI/min/ml) | 17,271.05 ± 9064.23 | 14,993.47 ± 9471.56 | 0.55 |
AUC C peptide (ng/min/ml) | 838.3 ± 306.8 | 841.98 ± 352.7 | 0.97 |
HDL cholesterol (mg/dl) | 46.66 ± 10.1 | 49.7 ± 12.8 | 0.37 |
Triglycerides (mg/dl) | 92.26 ± 52.5 | 88.55 ± 50.3 | 0.83 |
C-reactive protein (mg/dl) | 0.41 ± 0.7 | 0.33 ± 0.3 | 0.72 |
IGF-I SDS | −0.66 ± 0.9 | 0.03 ± 1.3 | 0.04 |