Table 3 Differences in plasma proteome among infants who developed BPD vs. those who did not develop this disease, before and after adjustment for gestational age, assessed at 36 PMA
UniProt Protein Name | UniProt accession | Ratio | p value for multiple comparisons | Ratio adjusted for GA | p adjusted for GA and multiple comparisons |
|---|---|---|---|---|---|
Alpha-2-antiplasmin | P08697 | 0.902954091 | 0.009571493 | 1.07 | 0.652 |
Alpha-fetoprotein | P02771 | 1.205017172 | 1.48E-06 | 1.073 | 0.651 |
Apolipoprotein A-I | P02647 | 0.921011303 | 0.000666248 | 0.97 | 0.851 |
Apolipoprotein A-IV | P06727 | 0.929138146 | 0.00183834 | 0.91 | 0.771 |
Carboxypeptidase N subunit 2 | P22792 | 0.913686152 | 0.034019428 | 0.859 | 0.343 |
CD44 antigen | P16070 | 0.857799986 | 0.001787237 | 1.111 | 0.514 |
Clusterin | P10909 | 1.134578843 | 0.000701756 | 1.043 | 0.733 |
Complement C1r subcomponent | P00736 | 0.900163532 | 0.040257434 | 0.976 | 0.884 |
Complement C1s subcomponent | P09871 | 0.858210146 | 2.42E-06 | 1.018 | 0.911 |
Corticosteroid-binding globulin | P08185 | 1.097266083 | 0.048487179 | 1.037 | 0.707 |
Fibrinogen gamma chain | P02679 | 1.073909534 | 0.049721103 | 1.154 | 0.309 |
Galectin-3-binding protein | Q08380 | 0.859983677 | 9.90E-05 | 0.786 | 0.025 |
Gelsolin | P06396 | 0.886021433 | 8.90E-05 | 0.953 | 0.708 |
Haptoglobin | P00738 | 1.484385427 | 5.56E-05 | 1.286 | 0.478 |
Hemoglobin subunit beta | P68871 | 1.250987956 | 0.000612418 | 1.114 | 0.329 |
Hemoglobin subunit gamma-1 | P69891 | 0.804233584 | 0.007778202 | 0.776 | 0.038 |
Immunoglobulin heavy constant gamma 1 | P01857 | 0.854508568 | 0.017674648 | 1.22 | 0.369 |
Immunoglobulin heavy constant gamma 3 | P01860 | 0.889487254 | 0.027804083 | 0.982 | 0.9583 |
Immunoglobulin lambda constant 2; Immunoglobulin lambda constant 3 | P0CG06 | 0.762467463 | 0.040257434 | 0.919 | 0.543 |
Immunoglobulin lambda-like polypeptide 5 | B9A064 | 0.881285593 | 0.029037441 | 1.024 | 0.811 |
Inter-alpha-trypsin inhibitor heavy chain H2 | P19823 | 0.924508903 | 0.001365124 | 0.988 | 0.924 |
Kininogen-1 | P01042 | 1.058078701 | 0.03628071 | 1.134 | 0.319 |
Leucine-rich alpha-2-glycoprotein | P02750 | 1.166917588 | 0.002032426 | 1.224 | 0.278 |
Osteopontin | P10451 | 0.872885059 | 0.027176592 | 0.982 | 0.92 |
Serotransferrin | P02787 | 1.123191657 | 4.19E-06 | 1.284 | 0.023 |
Transthyretin | P02766 | 1.183233993 | 0.017525513 | 1.122 | 0.432 |
Vitronectin | P04004 | 1.084990139 | 0.035870579 | 0.951 | 0.717 |