Table 5 Second-generation anti-H1 anti-histamine for children
From: Management of chronic urticaria in children: a clinical guideline
Second-generation H1-antihistamines | Pharmaceutical form | Age and/or weight | Dose |
|---|---|---|---|
Cetirizine | Drops 10 mg/ml (1 drop = 0,5 mg) Oral solution 1 mg/ml Tablets 10 mg | 2–6 years | 2.5 mg b.i.d. |
6–12 years | 5 mg b.i.d. | ||
12–18 years | 10 mg q.d. | ||
Loratadine | Syrup 1 mg/ml Tablets 10 mg | 2–12 years (< 30 kg) | 5 mg q.d. |
2–12 years (> 30 kg) | 10 mg q.d. | ||
12–18 years | 10 mg q.d. | ||
Fexofenadine | Tablets 120 mg Tablets 180 mg (Tablets/syrup 30 mg in US/UK) | 12–18 years (US> 2 years, UK > 6 years) | 120–180 mg q.d. 30 mg q.d. |
Levocetirizine | Drops 5 mg/ml (1 drop = 0,25 mg) Tablets 5 mg | 2–6 years (in US > 6 months) | 1.25 mg q.d. |
> 6 years | 5 mg q.d. | ||
Desloratadine | Oral solution 0,5 mg/ml Tablets 2.5 mg Tablets 5 mg | 1–5 years | 1.25 mg q.d. |
6–11 years | 2.5 mg q.d. | ||
> 12 years | 5 mg q.d. | ||
Acrivastine | Syrup 8 mg/10 ml Tablets 8 mg | > 12 years | 8 mg t.i.d. |
Rupatadine | Oral solution 1 mg/ml Tablets 10 mg | 2–11 years (< 25 kg) | 2.5 mg q.d. |
2–11 years (> 25 Kg) | 5 mg q.d. | ||
> 12 years old | 10 mg q.d. | ||
Bilastine | Syrup 2.5 mg/ml Tablets 10 mg Tablets 20 mg | > 6 years (> 20 kg) | 10 mg q.d. |
> 12 years | 20 mg q.d. | ||
Ebastine | Tablets 10 mg Tablets 20 mg (Syrup 5 mg/ml) | > 12 years (> 2 aa in Europe) | 10–20 mg q.d. (0.2 mg/kg q.d.) |